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Study of Incidence and Severity of Coronary Artery Stenosis at Autopsy

Rahul A. Mehta,, Ina Patel, Kuldip Teraiya

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Indian Journal of Forensic Medicine and Pathology 18(3):p 449-454, July-Sep 2025. | DOI: https://doi.org/10.21088/ijfmp.0974.3383.18325.3

How Cite This Article:

Patel I, Teraiya K, Mehta RA. Study of Incidence and Severity of Coronary Artery Stenosis at Autopsy. Indian J Forensic Med Pathol. 2025;18(3):159-64.

Timeline

Received : May 09, 2025         Accepted : July 23, 2025          Published : September 30, 2025

Abstract

Backgrounds: The occurrence of sudden cardiac death (SCD) has been continuously rising globally. Identification of modifiable risk factors may help reduce the incidence of sudden cardiac death. Aims: This study aimed to evaluate the incidence, associated risk factors, myocardial ischemic changes, and the specific arterial involvement in individuals who died due to a cardiac event. Material and method: The study was conducted at the Department of Forensic Medicine, Shri M. P. Shah Govt. Medical College, Jamnagar, from January 2023 to December 2023. A total of 110 cases of sudden death were included in the study. The heart was examined in these cases for both gross and myocardial analysis. Results: Left anterior descending artery (27.27%) was the most common site of stenosis, followed by left main artery (13.63%). The main feature was softening (8.18%) of myocardium, followed by hyperemia (4.54%) and myocardial fibrosis (3.63%) in the cases showing gross changes of ischemia. Conclusion: Sudden death caused by acute myocardial infarction mainly affects middle-aged individuals, with an increasing trend in younger people. The most common artery affected by stenosis was the left anterior descending artery, with most cases showing grade-3 or grade-4 stenosis. The left lateral wall is the most common site of infarction. Hypertension, Diabetes, nicotine consumption and drinking habits are the major risk factors. Nicotine and drinking habits can accelerate the development of coronary artery stenosis.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Patel I, Teraiya K, Mehta RA. Study of Incidence and Severity of Coronary Artery Stenosis at Autopsy. Indian J Forensic Med Pathol. 2025;18(3):159-64.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
May 09, 2025 July 23, 2025 September 30, 2025

DOI: https://doi.org/10.21088/ijfmp.0974.3383.18325.3

Keywords

Sudden cardiac deathRisk factorsCoronary stenosisCoronary heart disease

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Received May 09, 2025
Accepted July 23, 2025
Published September 30, 2025

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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