Anisha TS Assistant Professor, Department of Pathology, RajaRajeswari Medical College and Hospital, Bangalore, Karnataka 560074, India., India
Shashikala K2 Associate Professor,Department of Pathology, RajaRajeswari Medical College and Hospital, Bangalore, Karnataka 560074, India., India
Ramya T null Post Graduate Student Department of Pathology, RajaRajeswari Medical College and Hospital, Bangalore, Karnataka 560074, India, India
Address for correspondence: Anisha TS, Assistant Professor, Department of Pathology, RajaRajeswari Medical College and Hospital, Bangalore, Karnataka 560074, India., India E-mail: null
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AnishaTS, Shashikala K, Ramya T et al. Patterns of Lung Lesions in Autopsy: A Histopathological Study. Indian J Forensic Med Pathol. 2020;13(1):9-13
Timeline
Received : January 02, 2020
Accepted : February 02, 2020
Published : March 30, 2020
Abstract
Introdution: Autopsy is recognized as a necessary part of medicine to establish final diagnosis,
and relate the cause of death to the associated pathologies and the interaction between the two.
Aim: To study and highlight the histopathological changes in lungs seen in autopsy cases.
Methods: A cross-sectional study was done in the department of Pathology in a tertiary care
hospital in Bangalore. A total of 100 lung specimens received from the department of forensic
medicine for clinical autopsy over 3 years (January 2016 to January 2019) were studied. After
noting the patient details and autopsy findings, the specimens were examined grossly and
based on the gross findings, representative bits were given for histopathological examination.
The histopathological findings were noted and results were statistically analyzed.
Results: Amongst the 100 lungs studied, the commonest lesion was Congestion and/
Pulmonary edema (64%), followed by non-tuberculous pneumonia (15%), chronic bronchitis
(5%), emphysema (4%), tuberculous pneumonia (4%), autolytic changes (2%), pulmonary
embolism (2%), lung abscess (1%) and an immature lung (1%).
Conclusion: This study highlights the various lesions in lungs from patients with history of
varied causes of death and the lung lesions contributing directly or indirectly to the cause of
death.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
Whether all authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
The authors report no conflicts of interest in this work.
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AnishaTS, Shashikala K, Ramya T et al. Patterns of Lung Lesions in Autopsy: A Histopathological Study. Indian J Forensic Med Pathol. 2020;13(1):9-13
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator
Ditribution of cases based on the clinical history
Description: No description available.
Distribution of cases based on histopathology diagnosis
Description: No description available.
Photomicrographs show lung with features of congestion and presence of heart failure cells (hemosiderin laden macrophages) within the alveoli. Fig. A [H&E, 100X], Fig. B [H&E, 400X]
Description: No description available.
Photomicrographs show lung with features of lobar pneumonia. Fig. A [H&E, 100X], Fig. B [H&E, 400X]
Description: No description available.
Photomicrographs show features of chronic bronchitis. (A & B) Bronchi with increased mucous glands (arrow) and presence of chronic inflammatory infiltrate within the bronchi. Fig. A [H&E, 100X], Fig. B [H&E, 400X]
Description: No description available.
(A) Photomicrograph show caseous necrosis [H&E, 100X], (B & C) Photomicrographs show presence of granulomas with epithelioid cells (large arrow) and Langhans giant cell (arrow head) [H&E, 100X], (D) Photomicrograph show a well formed granuloma with epithelioid cells and central necrosis (arrow) [H&E, 400X]
Description: No description available.
Shows gross picture of lung with the presence of multiple grey white nodules in the lower lobe (arrow), from a patient who was a known case of pulmonary tuberculosis
Description: No description available.
(A & B) Photomicrographs show lung with emphysematous changes [H&E, 100X]
Description: No description available.
Photomicrograph of pulmonary emboli. (A) shows a pulmonary vessel with an embolus [H&E, 100X], (B) shows lines of zahn [H&E, 400X].