Durre Aden Assistant Professor, Department of Pathology, Hamdard Institute of Medical Sciences & Research, Jamia Hamdard, New Delhi, India
Soumya Tiwari Senior Resident, Department of Pathology, Hamdard Institute of Medical Sciences & Research, Jamia Hamdard, New Delhi, India
Zeeba S Jairajpuri Professor, Department of Pathology, Hamdard Institute of Medical Sciences & Research, Jamia Hamdard, India
Nehal Ahmed Associate Professor, Department of Pathology, Hamdard Institute of Medical Sciences & Research, Jamia Hamdard, New Delhi, India
Address for correspondence: Durre Aden, Assistant Professor, Department of Pathology, Hamdard Institute of Medical Sciences & Research, Jamia Hamdard, New Delhi, India E-mail: durre.aden@gmail.com
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Soumya Tiwari, Durre Aden, Zeeba S Jairajpuri et al. Histopathological Insights into Angioleiomyoma of the Nasal Cavity. Ind
Jr of Path: Res and Practice 2024;13(3)107-110.
Timeline
Received : November 27, 2024
Accepted : December 11, 2024
Published : December 30, 2024
Abstract
Angioleiomyoma (ALM) is a rare soft-tissue tumour with an overall prevalence of fewer than 100 cases reported so far. ALMs are well-defined, painless, slow-growing lesions, making preoperative differentiation from leiomyomas or other mesenchymal tumorsdifficult. We present here a case of a 24-year-old female with an exophytic, cystic swelling in the nasal cavity clinically suspected to be a nasolabial cyst. Surgical excision is the primary treatment of ALM, with a low
recurrence rate and only one reported case of malignant transformation to this date. This case highlights the importance of considering this rare benign lesion in the list of differential diagnoses for a fairly common complaint of sinonasal swelling and the definitive role of histopathology alongwith IHC for diagnosing such tumors.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Soumya Tiwari, Durre Aden, Zeeba S Jairajpuri et al. Histopathological Insights into Angioleiomyoma of the Nasal Cavity. Ind
Jr of Path: Res and Practice 2024;13(3)107-110.
This license
enables reusers to distribute, remix, adapt, and build upon the material in any
medium or format for noncommercial purposes only, and only so long as
attribution is given to the creator.
This license
enables reusers to distribute, remix, adapt, and build upon the material in any
medium or format for noncommercial purposes only, and only so long as
attribution is given to the creator.
Description: Microphotographs of the tumor show cellular lesion comprising of smooth muscle cells showing interlacing patterns with collagen fibres in between and presence of several thin walled dilated congested vascular channels between the fascicles. (H and E stain a. 10X; b. 10X; c. 40x; d. 40X)