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Review Article

Deep Vein Thrombosis: A Comprehensive Review

Anjum Abbasi, Vineet Rebeiro, Adil Hussain, Vinod Bhatt

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Indian Journal of Surgical Nursing 15(1):p 21-26, Jan-April 2026. | DOI: 10.21088/ijsn.2277.467X.15126.5

How Cite This Article:

Rebeiro V, Hussain A, Abbasi A, et al. Deep vein thrombosis: a comprehensive review. J Surg Nurs. 2026;15(1):21-26.

Timeline

Received : October 06, 2025         Accepted : November 12, 2025          Published : April 30, 2026

Abstract

Deep vein thrombosis (DVT) is a significant vascular condition characterized by the formation of blood clots within the deep venous system, most commonly affecting the lower extremities. It represents a major public health concern due to its association with morbidity, mortality, and long-term complications such as pulmonary embolism and post-thrombotic syndrome. Nursing professionals play a pivotal role in prevention, early recognition, patient education, and management of DVT. This review provides an in-depth exploration of epidemiology, risk factors, pathophysiology, clinical manifestations, diagnostic approaches, and management strategies, with a particular focus on the implications for nursing education and practice. By synthesizing current evidence and highlighting emerging trends, this article aims to strengthen nursing faculty’s knowledge base, support clinical decision-making, and enhances teaching effectiveness in preparing future nurses to manage patients at risk for or affected by DVT.


References

  • 1.   Ageno W, Becattini C, Brighton T, Selby R, Kamphuisen PW. Epidemiology and risk factors of venous thromboembolism. Semin Thromb Hemost. 2012;38(6):614-22.
  • 2.   Anderson FA, Spencer FA. Risk factors for venous thromboembolism. Circulation. 2003;107(23 Suppl 1):I9-I16.
  • 3.   Becattini C, Agnelli G, Schenone A. Aspirin for preventing the recurrence of venous thromboembolism. N Engl J Med. 2012;366(21):1959-67.
  • 4.   Cushman M. Epidemiology and risk factors for venous thrombosis. Semin Hematol. 2007;44(2):62-9.
  • 5.   Di Nisio M, van Es N, Büller HR. Deep vein thrombosis and pulmonary embolism. Lancet. 2016;388(10063):3060-73.
  • 6.   Farge D, Frere C, Connors JM, Ay C, Khorana AA, Munoz A, et al. International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer. Lancet Oncol. 2019;20(10):e566-e581.
  • 7.   Galanaud JP, Kahn SR, Wells PS, Anderson FA, Chagnon I, Le Gal G, et al. Predictive factors for recurrent venous thromboembolism. Thromb Res. 2018;163:6-11.
  • 8.   Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, et al. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008;133(6 Suppl):381S-453S.
  • 9.   Heit JA. Epidemiology of venous thromboembolism. Nat Rev Cardiol. 2015;12(8):464-74.
  • 10.   Kahn SR, Lim W. Prevention of VTE in nonsurgical patients. Chest. 2021;160(6):2129-40.
  • 11.   Kakkos SK, Gohel M, Baekgaard N, Belramman A, Draxler S, Elias A, et al. European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the management of venous thrombosis. Eur J Vasc Endovasc Surg. 2021;61(1):9-82.
  • 12.   Kesieme E, Kesieme C, Jebbin N, Irekpita E, Dongo A. Deep vein thrombosis: a clinical review. J Blood Med. 2011;2:59-69.
  • 13.   Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J. 2020;41(4):543-603.
  • 14.   Lyman GH, Carrier M, Ay C, Pontes KRSR, Levine MN, Khorana AA, et al. Venous thromboembolism prophylaxis and treatment in patients with cancer: ASCO guideline update. J Clin Oncol. 2021;39(12):1326-49.
  • 15.   Prandoni P, Villalta S. Venous thromboembolism and the post-thrombotic syndrome: prevention and treatment. Vasc Health Risk Manag. 2011;7:557-64.
  • 16.   Raskob GE, Angchaisuksiri P, Blanco AN, Buller H, Gallus A, Hunt BJ, et al. Thrombosis: a major contributor to global disease burden. Arterioscler Thromb Vasc Biol. 2018;38(12):3023-6.
  • 17.   Schünemann HJ, Cushman M, Burnett AE, Kahn SR, Holbrook A, Murad MH, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients. Blood Adv. 2018;2(22):3198-225.
  • 18.   Thaler J, Ay C. Venous thromboembolism: epidemiology, risk factors, and genetics. Hamostaseologie. 2020;40(6):366-74.
  • 19.   Wells PS, Anderson DR, Rodger M, Forgie M, Kearon C, Dreyer J, et al. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. N Engl J Med. 2003;349(13):1227-35.
  • 20.   Wendelboe AM, Raskob GE. Global burden of thrombosis: epidemiologic aspects. Circ Res. 2016;118(9):1340-7.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Rebeiro V, Hussain A, Abbasi A, et al. Deep vein thrombosis: a comprehensive review. J Surg Nurs. 2026;15(1):21-26.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
October 06, 2025 November 12, 2025 April 30, 2026

DOI: 10.21088/ijsn.2277.467X.15126.5

Keywords

Nursing ProfessionalDeep Vein ThrombosisBlood ClotPulmonary embolismPost-thrombotic syndrome

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Received October 06, 2025
Accepted November 12, 2025
Published April 30, 2026

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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