Background: Chronic kidney disease (CKD) has a significant impact on a person’s social, emotional, and physical health. Understanding the factors influencing the health-related quality life and lifestyle (HRQoL) of this demographic is crucial for
providing comprehensive patient care. Objectives: To investigate the main behavioral, psychological, clinical, and
sociodemographic factors that affect HRQoL in CKD patients. Methods: 280 CKD patients who visited nephrology clinics at three tertiary hospitals participated in a cross-sectional study. The Kidney Disease Quality of Life (KDQOL-36) questionnaire was used to measure HRQoL. Information was gathered on lifestyle factors, laboratory parameters, comorbidities, sociodemographics, and psychological distress (as measured by the Hospital Anxiety and Depression Scale). To find independent determinants of HRQoL, multiple linear regression was employed. Results: Reduced HRQoL was significantly correlated with depression (β = -0.42, p < 0.001), unemployment (β = -0.25, p = 0.02), lower education level (β = -0.21, p
= 0.03), diabetes (β = -0.27, p = 0.01), and physical inactivity (β = -0.19, p = 0.04). 61% of the variation in HRQoL was explained by the regression model (adjusted R2 = 0.61). Conclusion: In CKD patients, comorbid conditions, socioeconomic position, and psychological well-being have a major influence on HRQoL. To improve quality of life, integrated care that addresses both clinical and psychosocial aspects is advised. Author’
Original Article
English
P. 79-84