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Benign Prostatic Hyperplasia: A Comprehensive Evidence-Based Review of Etiopathogenesis, Clinical Spectrum, Diagnostic Modalities, Therapeutic Interventions and Nursing Management

Sneha null, Anjum Abbasi

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Indian Journal of Surgical Nursing 15(2):p 62-66, May - August 2026. | DOI: https://doi.org/10.21088/ijsn.2277.467X.15226.3

How Cite This Article:

Sneha, Anjum Abbasi. Benign Prostatic Hyperplasia: A Comprehensive Evidence-Based Review of Etiopathogenesis, Clinical Spectrum, Diagnostic Modalities, Therapeutic Interventions and Nursing Management. J Surg. Nurs. 2026; 15(2): 62-66.

Timeline

Received : April 23, 2026         Accepted : May 27, 2026          Published : August 30, 2026

Abstract

Background: Benign Prostatic Hyperplasia (BPH) is a chronic, progressive, nonmalignant enlargement of the prostate gland that commonly affects aging men. It is one of the leading causes of lower urinary tract symptoms (LUTS) worldwide and significantly influences physical comfort, psychological health, sleep quality, and overall quality of life. Aim: To critically analyze and synthesize current evidence regarding the etiology, risk factors, pathophysiology, clinical presentation, diagnostic evaluation, medical and surgical management, and comprehensive nursing care of BPH. Objectives: 1. To examine hormonal, inflammatory, and metabolic mechanisms contributing to BPH. 2. To describe symptom classification and disease progression. 3. To review contemporary diagnostic tools and investigations. 4. To evaluate pharmacological and surgical interventions. 5. To outline evidence-based nursing management strategies. Materials and Methods: A narrative review was conducted using peer-reviewed journals, urology guidelines, textbooks, and evidence-based online medical resources. Literature was analyzed systematically and synthesized in structured format. References are cited in Vancouver style. Results: BPH is strongly associated with aging, androgenic stimulation via dihydrotestosterone (DHT), chronic inflammation, and metabolic disturbances. Clinical manifestations range from mild urinary hesitancy to severe retention and renal compromise. Diagnosis involves digital rectal examination (DRE), prostate-specific antigen (PSA), uroflowmetry, imaging, and endoscopic assessment. Management includes alpha-adrenergic blockers, 5-alpha reductase inhibitors, minimally invasive therapies, and surgical interventions such as Transurethral Resection of the Prostate (TURP). Nursing care plays a critical role in monitoring urinary function, preventing complications, promoting fluid balance, and providing patient education. Conclusion: BPH is a multifactorial age-related condition requiring individualized, multidisciplinary management. Early identification and comprehensive nursing support significantly improve patient outcomes and reduce complications.


References

  • 1.   McVary KT. BPH epidemiology and pathophysiology. Urol Clin North Am. 2009;36:403-15.
  • 2.   Berry SJ, Coffey DS, Walsh PC. The development of human BPH with age. J Urol. 1984;132:474-9.
  • 3.   Roehrborn CG. BPH progression and complications. Rev Urol. 2005;7:S3-S14.
  • 4.   OpenStax. Anatomy and Physiology. 2019.
  • 5.   Nickel JC. Prostate zonal anatomy. Urology. 2008;72:S5-S8.
  • 6.   Roehrborn CG. Pathology of BPH. Int J Impot Res. 2008;20:S11-S18.
  • 7.   Prins GS, Korach KS. Estrogen role in prostate disease. Endocr Rev. 2008;29:567-91.
  • 8.   Nickel JC. Inflammation in BPH. Urology. 2008;72:1-7.
  • 9.   Parsons JK. Risk factors for BPH. Curr Opin Urol. 2010;20:1-5.
  • 10.   Kupelian V, et al. Metabolic syndrome and LUTS. J Urol. 2009;182:616-21.
  • 11.   Barry MJ, et al. IPSS development. J Urol. 1992;148:1549-57.
  • 12.   Thompson IM, et al. PSA interpretation. N Engl J Med. 2004;350:2239-46.
  • 13.   AUA Guidelines Panel. Management of BPH. 2018.
  • 14.   Tacklind J, et al. Serenoa repens for BPH. Cochrane Database Syst Rev. 2012.
  • 15.   Reich O, et al. TURP standard of care. Eur Urol. 2008;54:969-80.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Sneha, Anjum Abbasi. Benign Prostatic Hyperplasia: A Comprehensive Evidence-Based Review of Etiopathogenesis, Clinical Spectrum, Diagnostic Modalities, Therapeutic Interventions and Nursing Management. J Surg. Nurs. 2026; 15(2): 62-66.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
April 23, 2026 May 27, 2026 August 30, 2026

DOI: https://doi.org/10.21088/ijsn.2277.467X.15226.3

Keywords

Benign Prostatic HyperplasiaLower Urinary Tract SymptomsDHTTURPProstate EnlargementNursing Care

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Timeline


Received April 23, 2026
Accepted May 27, 2026
Published August 30, 2026

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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