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Comprehensive Analysis of Salivary Gland Lesions: Evaluating Spectrum in Tertiary Care through Fine Needle Aspiration Cytology

Mohibul Islam Ahmed, Mohammed Abdul Sameer, Deepak Sadhu, Reshma Wattamwar

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Indian Journal of Pathology: Research and Practice 12(4):p 131-135, October-December 2023. | DOI: https://doi.org/10.21088/ijprp.2278.148X.12423.2

How Cite This Article:

Mohibul Islam Ahmed, Mohammed Abdul Sameer, Deepak Sadhu, et al. Comprehensive Analysis of Salivary Gland Lesions: Evaluating Spectrum in Tertiary Care through Fine Needle Aspiration Cytology. Ind J Pathol: Res Pract. 2023;12(4) 131–135.

Timeline

Received : October 10, 2023         Accepted : November 21, 2023          Published : December 30, 2023

Abstract

Background: Salivary glands, pivotal for oral health, present diagnostic complexities with diverse pathologies, including neoplasms constituting 6% of head and neck tumors. FNAC proves to be a reliable and cost-effective diagnostic tool, proficient in discerning various salivary gland lesions. Aims: This study aims to comprehensively explore the spectrum of salivary gland lesions within a tertiary care center, emphasizing FNAC precision. Materials and Methods: This retrospective observational study, conducted at Dr. Shankarrao Chavan Government Medical College and Hospital, Nanded, from January 2021 to September 2023, aimed to comprehensively analyze 60 cases of suspected salivary gland lesions using FNAC. Results: This study examined 60 salivary gland tumor cases, finding a balanced gender distribution (51.67% males, and 48.33% females). Prevalence peaked in ages 31-40 (25%). Parotid (50.00%) and submandibular (43.33%) glands were primary tumor sites. Chronic sialadenitis (30%) dominated non-neoplastic lesions. Pleomorphic Adenoma dominated benign cases (21.67%), while Mucoepidermoid Carcinoma was the most common malignancy (3.33%). The sensitivity, specificity, and diagnostic accuracy for the neoplastic lesion were 75%, 100%, and 92.86% respectively. Conclusion: This study enhances understanding of the demographic and pathological landscape of salivary gland lesions highlighting the prevalence of non-neoplastic conditions like chronic sialadenitis and specific neoplasms, such as pleomorphic adenoma and mucoepidermoid carcinoma. FNAC remains pivotal for accurate diagnosis, emphasizing its ongoing role in clinical decision-making.


References

  • 1.   L. Barnes, J. W. Eveson, P. Reichart, and D. Sidransky. Pathology and genetics of head and neck tumors. In World Health Organization Classification of Tumors, P. Kleihues and L. H. Sobin, Eds., p. 210, IARC Press, Lyon, France, 2005.
  • 2.   Mavec P, Eneroth CM, Franzen S, Moberger G, Zajicek J. Aspiration biopsy of salivary gland tumors. Correlation of cytologic reports from 652 aspiration biopsies with clinical and histologic findings. Acta oto-laryngologica. 1964;58(1-6):471-84.
  • 3.   Franzen S, Zajicek J. Cytologic diagnosis on aspirates from 1000 salivary gland tumors. Acta Otolaryngol. 1970;224:168-72.
  • 4.   Shaha AR, Webber C, dimaio T, Jaffe BM. Needle aspiration biopsy in salivary gland lesions. Am J Surg. 1990;160:373-6.
  • 5.   Khandekar MM, Kavatkar AN, Patankar SA, Bagwan IB, Puranik SC, Deshmukh SD. FNAC of salivary gland lesions with histopathological correlation. Indian J Otolaryngol Head Neck Surg. 2006;58:246–8.
  • 6.   S. Nguansangiam, S. Jesdapatarakul, N. Dhanarak, and K. Sosrisakorn, “Accuracy of fine needle aspiration cytology of salivary gland lesions: routine diagnostic experience in Bangkok, Thailand.” Asian Pacific Journal of Cancer Prevention. 2012; 13(4):1583–1588.
  • 7.   Sonal Verma S. Fine needle aspiration cytology of salivary gland lesions: study in a tertiary care hospital of North Bihar. Int J Res Med Sci 2016;4:3869-72.
  • 8.   Mili Jain, Upasana Punatar, Sanyam Modi, Kuntal Patel. Role of FNAC in the diagnosis of salivary gland lesions - A tertiary care hospital experience. IAIM, 2022; 9(10): 27-31.
  • 9.   A.A Choudhury, T. Sultana, B.H. Siddique, and A. S. A. Amin, “Diagnosis of parotid gland mass by the fine needle aspiration cytology (FNAC) and its histopathological correlation 2 years study in BSMMU, Dhaka,” Bangabandhu Sheikh Mujib MedicalUniversity Journal, vol. 4, no. 2, pp. 65–69, 2011.
  • 10.   Singh Nanda KD, Mehta A, Nanda J. Fine needle aspiration cytology: A reliable tool in the diagnosis of salivary gland lesions. J Oral Pathol Med. 2012 Jan;41(1):106-12.
  • 11.   Gupta R, Dewan D, Kumar D, Suri J. Fine needle aspiration cytology of salivary gland lesions with histopathological correlation in a district hospital of Jammu region. Indian J Pathol Oncol. 2016 JanMar;3(1):32 7.
  • 12.   Gunvanti Rathod, Pragnesh Parmar. Fine needle aspiration cytology of swellings of head and neck region. Indian Journal of Medical Sciences, 2012; 66: 49-54.
  • 13.   Rathod GB, Ghadiya V, Shinde P, Tandan RK. Pleomorphic sarcoma in 60 years old male – A case report. International Journal of Current Microbiology and Applied Sciences, 2014; 3(8): 510-517.
  • 14.   Annie Jain, Gunvanti Rathod. Oncocytoma of the parotid gland: A rare case report. IAIM, 2015; 2(4): 166-169.
  • 15.   Nupur Singla, Gunvanti Rathod, Disha Singla. Adenoid cystic carcinoma of the parotid gland - A case report and review of literature. IAIM, 2015; 2(4): 182-186.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Mohibul Islam Ahmed, Mohammed Abdul Sameer, Deepak Sadhu, et al. Comprehensive Analysis of Salivary Gland Lesions: Evaluating Spectrum in Tertiary Care through Fine Needle Aspiration Cytology. Ind J Pathol: Res Pract. 2023;12(4) 131–135.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
October 10, 2023 November 21, 2023 December 30, 2023

DOI: https://doi.org/10.21088/ijprp.2278.148X.12423.2

Keywords

Salivary gland lesionsFine-needle aspiration cytology (FNAC)Tertiary careChronic sialadenitisPleomorphic adenomaMucoepidermoid carcinoma

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Received October 10, 2023
Accepted November 21, 2023
Published December 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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