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Case Report

Head and Neck Follicular Dendritic Cell Sarcoma: Report of Five Cases

Archana Lakshmanan, Annapurneswari Subramanyan

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Indian Journal of Pathology: Research and Practice 12(4):p 137-141, October-December 2023. | DOI: https://doi.org/10.21088/ijprp.2278.148X.12423.3

How Cite This Article:

Archana Lakshmanan, Annapurneswari Subramanyan. Head and Neck Follicular Dendritic Cell Sarcoma: Report of Five Cases. Ind J Pathol: Res Pract. 2023;12(4) 137–141.

Timeline

Received : October 23, 2023         Accepted : November 30, 2023          Published : December 30, 2023

Abstract

Follicular dendritic cells (FDC) are accessory cells which play a major role in antigen presentation. The neoplasms arising from FDC are very rare and have been in reported in both nodal and extra nodal locations. We report 5 cases of follicular dendritic cell sarcomas arising in the head and neck region. Three were nodal and two cases were extra nodal in location. The patients age ranged from 34-46 years. There were 3 males and 2 females. Two cases had multiple recurrences. Surgery was the main stay of treatment with some of them received adjuvant chemotherapy and radiotherapy. They showed varied morphology with spindle, epithelioid and pleomorphic appearances. Although these neoplasms are extremely rare, it is important to consider them in the differentials, thereby preventing misdiagnosis.

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.

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Cite this article

Archana Lakshmanan, Annapurneswari Subramanyan. Head and Neck Follicular Dendritic Cell Sarcoma: Report of Five Cases. Ind J Pathol: Res Pract. 2023;12(4) 137–141.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
October 23, 2023 November 30, 2023 December 30, 2023
DOI: https://doi.org/10.21088/ijprp.2278.148X.12423.3

Keywords

Dendritic cellsSarcomaFollicularAntigen presentation

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Timeline

Received October 23, 2023
Accepted November 30, 2023
Published December 30, 2023

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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