Ajit Pal Singh Associate Professor, Department of Medical Lab Technology, School of Medical and Allied Sciences, Galgotias University, Greater Noida, India., India
Javed Siddiqui Assistant Professor, Department of Medical Lab Technology, School of Medical and Allied Sciences, Galgotias University, Greater Noida, India, India
Vijay Singh Assistant Professor, Department of Medical Lab Technology, School of Medical and Allied Sciences, Galgotias University, Greater Noida, India, India
Address for correspondence: Ajit Pal Singh, Associate Professor, Department of Medical Lab Technology, School of Medical and Allied Sciences, Galgotias University, Greater Noida, India., India E-mail: ajitpal.singh@galgotiasuniversity.edu.in
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Singh AP, Siddiqui J, Singh V. Advanced Tissue Processing: Automation and Emerging Technologies. Ind Jr of Path: Res and Practice. 2026;15(1):21-38.
Timeline
Received : November 21, 2025
Accepted : December 25, 2025
Published : April 30, 2026
Abstract
Advanced tissue processing has experienced a significant transformation with the use of automation and developing technology, revolutionising histopathology and diagnostic procedures. Automated tissue processors now provide improved precision, repeatability, and throughput, markedly diminishing human error and turnaround time. Innovations including microwave-assisted processing, vacuum infiltration, and real-time process monitoring have enhanced the preservation of tissue shape and molecular integrity. Simultaneously, innovative technologies such as artificial intelligence (AI), digital pathology, and 3D bio printing are transforming tissue examination and interpretation, facilitating more personalised and data-driven diagnostics. These developments facilitate enhanced standardisation and scalability, especially in high-volume clinical and research environments. Furthermore, innovative reagents and eco-friendly techniques are being formulated to reduce hazardous exposure and environmental impact. The convergence of automation and innovation in tissue processing promises enhanced operational efficiency and profound insights into tissue architecture and disease causes, facilitating the advancement of next-generation precision medicine and therapeutic methods.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
Whether all authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
The authors report no conflicts of interest in this work.
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Cite this article
Singh AP, Siddiqui J, Singh V. Advanced Tissue Processing: Automation and Emerging Technologies. Ind Jr of Path: Res and Practice. 2026;15(1):21-38.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.