Indian Journal of Pathology: Research and Practice

Background: Hysterectomy is considered the gold standard gynaecological procedure and is performed all over the world for the treatment of benign and malignant disorders. Aim & Objective: To study the clinical indication, gross and histopathological feature of uterus and cervix in hysterectomy specimens and correlate with clinical finding. Material & Methods: A retrospective was conducted in Department of Pathology Aug 2020 to Aug 2022. A total duration of the study was two years. The gross and histopathological findings of 70 hysterectomy specimens received in the department of pathology. Surgical specimens were fixed in formalin and tissues were adequately processed from them and stained with hematoxylin and eosin. A thorough microscopic examination of the stained slide were carried out & a histopathological diagnosis was made. The histopathological findings of the hysterectomy specimen were noted and then correlated with the clinical findings. Results: A clinicopathological correlation was noted in 70 cases. The endomyomatrium was the most commonly seen in 39 cases, the cervix 20 cases and ovary 11 cases. The incidence of chronic cervicitis was high, followed by squamous metaplasia, carcinoma of the cervix, nebothian cysts and cervical leiomyoma. The most common lesion among the endometrium was hyperplasia without atypia, followed by endometrial polyps, endometrium carcinoma, and atypical hyperplasia. Among the myomatrium lesions leiomyomas were the most common followed by adenomyosis. Among the ovarian lesions were simple cysts, corpus leuteal cysts, follicular cysts, fibroma, and serous cysteadenoma. Conclusion: This study found a good correlation between clinical indication and histopathology in benign and malignant pathologies. All the hysterectomy specimens should be sent for histopathological examination to ensure better post-operative management, especially in malignant diseases.

Elective surgery requires planned incisions, and these require appropriate blades. Major elective incisions are used for sectioning of skin, vessels, deeper tissue. The Colorado micro dissection needle was introduced into clinical practice with various applications. The concept of electrocautery incisions is fast gaining acceptance not only amongst the neurosurgeons, but also the plastic surgeons, orthopedics, the general surgeons for thoracic and abdominal incisions and the myths behind its complications are soon fading with excellent result. This article reviews colaradomicrodissection needle in all aspects.

Gastrointestinal involvement of endometriosis has been found in 6%- 10% of reproductive age group women and exclusive localization on the ileum is very rare (1%-7%). Endometriosis is characterized by the presence of endometrial tissue consisting of glands and/or stroma located outside the uterus. When the terminal ileum is affected by endometriosis, the entity distinction from other diseases of the ileocecal region is difficult in terms of clinical presentation, symptomatology and radiological appearance. Histological assessment after resection of the involved small bowel segment in the three patients shows a final diagnosis of ileal endometriosis with confirmation by Immunohistochemistry which shows ER, PR and CD10 positive.

Mucormycosis is aggressive and potentially fatal in patients particularly among diabetic patients suffering from ketoacidosis. A 16 year female patient came to medicine department with a complaint of fever since 15 days, cough and breathlessness and chest pain and palpitation since 10 days also having left orbital and facial swelling since 3 days. Patient is known case of type 2 diabetes mellitus. On CT Scan PNS (Plain) showed a soft tissue thickening causing complete opacification of left maxillary sinus extending to left frontal, left ethmoid and left hemisphenoid sinuses. The treatment of debridement of necrotic tissue from left maxillary sinus was done. On histopathology diagnosed as invasive mucormycosis. We are presenting this case of mucormycosis in a diabetic patients suffering from ketoacidosis for its the clinical, radiological, histopathological findings and management of the disease. Early diagnosis and prompt treatment significantly improves survival and decreases morbidity.