Abstract

Mucormycosis is aggressive and potentially fatal in patients particularly among diabetic patients suffering from ketoacidosis. A 16 year female patient came to medicine department with a complaint of fever since 15 days, cough and breathlessness and chest pain and palpitation since 10 days also having left orbital and facial swelling since 3 days. Patient is known case of type 2 diabetes mellitus. On CT Scan PNS (Plain) showed a soft tissue thickening causing complete opacification of left maxillary sinus extending to left frontal, left ethmoid and left hemisphenoid sinuses. The treatment of debridement of necrotic tissue from left maxillary sinus was done. On histopathology diagnosed as invasive mucormycosis. We are presenting this case of mucormycosis in a diabetic patients suffering from ketoacidosis for its the clinical, radiological, histopathological findings and management of the disease. Early diagnosis and prompt treatment significantly improves survival and decreases morbidity.

• 1.   Auluck A.Maxillary necrosis by mucormycosis. A case report and literature review. Med Oral Patol Oral Cir Bucal. 2007, 1; 12(5):E360-4.
• 2.   Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005,1;41(5):634-53.
• 3.   Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clinical Infectious Diseases. 2012,1;54(suppl- 1): S23-34.
• 4.   Sunil VJ, Swati SJ, Atul H, Snigdha AV, Divya B, Shubhang M. COVID-19 Associated Mucormycosis (CAM): A Clinico Histopathological Study of at A Tertiary Care Centre.Indian Journal of Pathology: Research and Practice. 2022; 11,1:19-26.
• 5.   Jeong W, Keighley C, Wolfe R, et al. The epidemiology and clinical manifestations of mucormycosis: a systematic review and metaanalysis of case reports. Clin Microbiol Infect. 2019;25:26–34.
• 6.   Jagtap SV, Jagtap SS, Nagar V, Varshney K . Invasive mucormycosis in post COVID-19 infection: Case report with review. IP Arch Cytol Histopathol Res .2021;6(2):135-139.
• 7.   Karadeniz Uğurlu Ş, Selim S, Kopar A, Songu M. Rhino-orbital Mucormycosis: Clinical Findings and Treatment Outcomes of Four Cases. Turk J Ophthalmol. 2015;45(4):169-174.
• 8.   Bavikar P, Mehta V. Rhino-orbital-cerebral Mucormycosis: a fatal complication of uncontrolled diabetes mellitus. Cureus. 2017;9(11):e1841.
• 9.   Jagtap SV, Hulwan A, Vartak S et.al. Co-infection of mucormycosis and actinomycosis in COVID-19 infection. Int J Health Sci Res. 2021; 11(8): 127-130.
• 10.   Galletti B, Gazia F, Galletti C, Perani F, Ciodaro F, Freni F, et al. Rhinocerebral mucormycosis with dissemination to pontine area in a diabetic patient: Treatment and management. Clin Case Rep. 2019;7(7):1382–7.
• 11.   Bhansali A, Bhadada S, Sharma A, et al.Presentation and outcome of rhino-orbital-cerebral mucormycosis in patients with diabetes. Postgraduate Medical Journal. 2004;80:670-674.

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