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Indian Journal of Forensic Medicine and Pathology 17(4):p 293-296, OCT. DEC. 2024. | DOI: https://doi.org/10.21088/ijfmp.0974.3383.17424.11
Case Report
Use of Hospital-Based Blood Gas Analyzer for Diagnosis of Carbon Monoxide Poisoning in Medicolegal Autopsy Cases: An Experience from Series of Cases
Jagruti J. Nikam, H.S. Tatiya, H.V. Vaidya, V.T. Jadhao
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Forensic Medicine and Pathology 17(4):p 293-296, OCT. DEC. 2024. | DOI: https://doi.org/10.21088/ijfmp.0974.3383.17424.11
How Cite This Article:
Nikam JJ, Tatiya HS, Vaidya HV, et al. Use of Hospital-Based Blood Gas Analyzer for Diagnosis of Carbon Monoxide Poisoning in Medicolegal Autopsy Cases: An Experience from Series of Cases. Indian J Forensic Med Pathol. 2024;17(4):293-296.Timeline
Received : September 20, 2024
Accepted : December 11, 2024
Published : December 15, 2024
Abstract
Cases of carbon monoxide (CO) poisoning are challenging for toxicology laboratories, on the other hand immediate confirmation of CO poisoning is sometimes very essential for investigating agencies. Though autopsy findings are self-sufficient for this confirmation, a laboratory validation adds more weightage. Currently, in many of our Regional Forensic Science Laboratories (RFSL), spectrophotometric analysis is used for the detection of Carboxy-haemoglobin (COHb). However, samples being susceptibile to alterations of optical state and degradation during sampling, transport and storage pose difficulties in analysis. Secondly reports from RFSL are received after much longer durations. However, hospitalbased blood gas analyzers with CO-oximetry, provide automated spectrophotometric measurement of concentration of total haemoglobin (ctHb) in blood along with that of other four haemoglobin derivatives and COHb levels, that too immediately and at a low cost. Over the background of delayed reporting from RFSL, we hereby discuss five cases of CO poisoning, confirmed with the help of hospital-based blood gas analyser.
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Data Sharing Statement
There are no additional data available.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to thank, Dr. Abhay Jagtap, Associate Professor, Department of Biochemistry, BJGMC, Pune, for his valuable help in making us understand the functionality of hospital-based ABG Machine. We would also like to extend our thanks to Dr. Deepak Joshi, Dy Director, RFSL, Pune for his prompt response to queries regarding the methodology used forthe determination of COHb at RFSL, Pune.
Conflicts of Interest
The authors report no conflicts of interest in this work.
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Cite this article
Nikam JJ, Tatiya HS, Vaidya HV, et al. Use of Hospital-Based Blood Gas Analyzer for Diagnosis of Carbon Monoxide Poisoning in Medicolegal Autopsy Cases: An Experience from Series of Cases. Indian J Forensic Med Pathol. 2024;17(4):293-296.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| September 20, 2024 | December 11, 2024 | December 15, 2024 |
DOI: https://doi.org/10.21088/ijfmp.0974.3383.17424.11
Keywords
Postmortem blood sampleHospital-based ABG machineCOHbCO-oximetrySpectrophotometrySearch for Similar Articles
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Timeline
| Received | September 20, 2024 |
| Accepted | December 11, 2024 |
| Published | December 15, 2024 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
