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Pattern of Congenital Anomalies: A Hospital Based Fetal Autopsy Study

Parameswari Babu. U. , Ranga Rao D.1 null, Kalyan K.3 null, Muni Bhavani I.4 null

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Indian Journal of Forensic Medicine and Pathology 11(2):p 106-110, April-June 2018. | DOI: 10.21088/ijfmp.0974.3383.11218.11

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Received : February 10, 2018         Accepted : February 26, 2018          Published : March 30, 2018

Abstract

Congenital malformations are most common cause of perinatal death. Antenatal imaging studies can easily detect the problem, and can give an idea of diagnosis. However autopsy still plays a pivotal role in confirming the diagnosis and identifying actual cause of fetal loss. Materials And Methods: This is a descriptive, cross-sectional study on 101 fetuses, over a period of 2 years from October 2014 to September 2016 referred to the Department of Pathology, Dr PSIMS & RF; which were an outcome of spontaneous abortions, intrauterine deaths, still births and of therapeutic abortions due to anomalies. This study is to determine overall incidence and distribution of various congenital anomalies and data was analyzed statistically. Results: Total 101 consecutive perinatal autopsy were performed, 31 (30.6%) fetuses showing congenital anomalies with female (16.8%) predominance and M:F ratio 1:1.2. Common congenital anomalies were observed in this study included central nervous system defects - anencephaly and meningomyelocele being common. Other systemic anomalies are genitourinary system, gastrointestinal system, respiratory and musculoskeletol system were seen. Multiple syndromes such as Prune-belle, Meckel- gruber were observed in this study.

References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.

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Cite this article

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.

Received Accepted Published
February 10, 2018 February 26, 2018 March 30, 2018
DOI: 10.21088/ijfmp.0974.3383.11218.11

Keywords

Perinatal AutopsyCongenital Anomalies

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Timeline

Received February 10, 2018
Accepted February 26, 2018
Published March 30, 2018

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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