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Organogenesis & Histogenesis of Spleen in Human Foetuses at Different Weeks of Gestation

Amit P. Tirpude, Assistant Professor, Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar, Odisha 751019, India. , Arpan Haldar1 , Amit P. Tirpude2 , Manisha R. Gaikwad3 , Soumya Chakraborty4 , Provas Banerjee5

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Indian Journal of Anatomy 7(5):p 490-497, Sep-Oct 2018. | DOI: http://dx.doi.org/10.21088/ija.2320.0022.7518.5

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Abstract

Spleen is the organ of anatomic & functional component of reticulo­ endothelial system & functions as a complex filter interposed in blood stream. Haematopoietic function of spleen continues & regresses after birth but production of lymphocytes continues in post­natal life. This study was done to correlate the chronological pattern of spleen development in this geographical eastern region of India, Odisha & compare the results from other researchers nationwide & worldwide. Aborted human foetuses without obvious congenital anomaly of gestational age between 12 weeks and 36 weeks were collected and processed for histology by H/E stain to note the differences of fetal spleen with the adult spleen.

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DOI: http://dx.doi.org/10.21088/ija.2320.0022.7518.5

Keywords

Spleen; Organogenesis; Reticulo­Endothelial System; Lymphocytes; Haematopoietic.

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