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Non- Neoplastic Lesions in Nephrectomy Specimens: A Histopathological Study

Harshanand S., Tutor, Dept. of Pathology, Gulbarga Institute of Medical Sciences (GIMS), Kalaburagi, Karnataka 585101, India. , Harshanand S.1 , Chandrakanth V.R.2 , Jayashree K.3 , Bharath C.4

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Indian Journal of Pathology: Research and Practice 7(4):p 493-499, April 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.15

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Abstract

Introduction: Nephrectomy is a common procedure in urological practice. Simple nephrectomy is indicated in patients with an irreversible damaged kidney resulting from symptomatic chronic infections, obstruction, calculus, severe traumatic injury and renal dysplasia. The present study was aimed at studying of wide spectrum of renal diseases, to study the frequency of non neoplastic conditions and correlation with respect to age and sex of the patients.

Methodology: The study was prospective and included 40 nephrectomy specimens over a period of 2 years. The gross morphology and the microscopic features were studied.

Results: In the present study, a total of 40 cases of nephrectomy specimens were studied. Of the 40 cases, 25 were non-neoplastic lesions (62.5%).

Conclusion: It is mandatory for every nephrectomy specimen to be subjected, to a detailed Histopathological examination, for a clinico-pathological correlation to ensure proper management. The clinical outcomes of various histologic subtypes are different, validating for accurate subtyping of renal lesions in clinical practice. Chronic Pyelonephritis was the commonest non-neoplastic lesion in females, which is a consistent finding in the present study. No significant difference was noted in the frequency of males and females in case of other non-neoplastic lesions of kidney.

Keywords: Nephrectomy; Chronic Pyelonephritis; Renal Cell Carcinoma.

 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.15

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