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Indian Journal of Pathology: Research and Practice

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Cytomorphological Features in Fine Needle Aspiration Cytology (FNAC) of Non-Neoplastic Lymph Node Lesions

S.S. Hiremath, Professor, Department of Pathology, S. Nijalingappa Medical College, Navanagar, Bagalkot, Karnataka-587101, India. , Harika Mandava1 , S.S. Hiremath2 , S.S. Inamdar3 , Deepak Gopinath4

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Indian Journal of Pathology: Research and Practice 7(4):p 488-492, April 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.14

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Abstract

Introduction: Lymphadenopathy is a commonly encountered clinical problem. Fine needle aspiration cytology offers immediate preliminary diagnosis. In routine practice <1% of patients with peripheral lymphadenopathy will be having malignant process. This necessitates the study on non-neoplastic lesions of lymph node.

Objectives: 1. To study the spectrum of non-neoplastic lymph node lesions diagnosed by FNAC
2.To study cytomorphological features of various non-neoplastic lymph node lesions by FNAC
3. To correlate with histopathology wherever possible

Methods: This was a two year study from January 2016 to December 2017 conducted in SNMC and HSK hospital and 286 patients with non-neoplastic lymph nodes were included in the study. Lymph node aspiration was done, smears were prepared, fixed, stained with H&E and Pap. Air dried smears were stained with Giemsa and ZN.

Results: The age ranging from 1 month to 85 years. Majority were reactive lymphadeniti (173/286) followed by tuberculous lymphadenitis (49/286), granulomatous lymphadenitis (22/286), acute suppurative lymphadenitis (34/286), Idiopathic necrotizing lymphadenitis (5/286), kimura’s disease (1/286),Rosai-Dorfman disease (1/286), filariasis (1/286). Histopathology was available in 26 cases of which 24 cases on biopsy confirmed the cytological diagnosis. Rest two cases were false negative. In remaining cases lymphadenopathy subsided with appropriate therapy.

Conclusion: FNAC is technically easy, rapid, cost-effective and reliable for diagnosing non-neoplastic lymph node lesions. Repeated aspirations will avoid sampling errors.

Keywords: FNAC; Non-Neoplastic Lymphnode; Lymphadenitis. 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7418.14

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