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Pediatric Education and Research 4(2):p 59-61, May-Aug 2016. | DOI: DOI: https://dx.doi.org/10.21088/per.2321.1644.4216.3
Original Article
Lactate Clearance as a Marker of Mortality in Paediatric Intensive Care Unit
Liza Bulsara* , Bipin Rathod* , Sunil Mhaske** , Liza Bulsara*
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Pediatric Education and Research 4(2):p 59-61, May-Aug 2016. | DOI: DOI: https://dx.doi.org/10.21088/per.2321.1644.4216.3
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Abstract
Objectives: To correlate lactate clearance with Pediatric Intensive Care Unit (PICU) mortality. ethods: 45 (mean age 40.15 mo, 60% males) consecutive admissions in the PICU were enrolled between January 2015 and December 2015. Lactate clearance (Lactate level at admission – level 6 hr later x 100 /lactate level at admission) in first 6 hours of hospitalization was correlated to inhospital mortality and PRISM score. Results: Twelve out of 45 patients died. 90% died among those with delayed/poor clearance (clearance <30%) compared to 8.5% in those with good clearance (clearance >30%) (P<0.001). Lactate clearance <30% predicted mortality with sensitivity of 75%, specificity of 97%, positive predictive value of 90%, and negative predictive value of 91.42%. Predictability was comparable to PRISM score >30. Conclusion: actate clearance at six hours correlates with mortality in the PICU.
Keywords: InHospital Mortality; Lactate Clearance; PRISM Score.
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DOI: DOI: https://dx.doi.org/10.21088/per.2321.1644.4216.3
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