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Invasive Mucormycosis in an Adolescent Female with Type-I Diabetes Mellitus

Sunil V Jagtap, Shubham S Jagtap, Devika Suresh Borade, Gauri Avinash Patil, Shuchita Gaur

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Indian Journal of Pathology: Research and Practice 12(1):p 29-33, January-March 2023. | DOI: 10.21088/ijprp.2278.148X.12123.4

How Cite This Article:

Jagtap SV, Jagtap SS, Borade DS, et al. Invasive mucormycosis in an adolescent female with type-I diabetes mellitus. Indian J Pathol Res Pract. 2023;12(1):29–33.

Timeline

Received : November 23, 2022         Accepted : December 28, 2022          Published : January 30, 2023

Abstract

Mucormycosis is aggressive and potentially fatal in patients, particularly among diabetic patients suffering from ketoacidosis. A 16-year female patient came to the medical department with a complaint of fever for 15 days, cough and breathlessness, chest pain, and palpitation for 10 days also had left orbital and facial swelling for 3 days. The patient is a known case of type 2 diabetes mellitus. On CT Scan PNS (Plain) showed a soft tissue thickening causing complete opacification of the left maxillary sinus extending to the left frontal, left ethmoid, and left he misphenoid sinuses. The treatment of debridement of necrotic tissue from the left maxillary sinus was done. On histopathology diagnosed as invasive mucormycosis. We are presenting this case of mucormycosis in diabetic patients suffering from ketoacidosis for its clinical, radiological, and histopathological findings and management of the disease. Early diagnosis and prompt treatment significantly improve survival and decreases morbidity. 


References

  • 1.   Auluck A. Maxillary necrosis by mucormycosis. A case report and literature review. Med Oral Patol Oral Cir Bucal. 2007;12(5):E360–4.
  • 2.   Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005;41(5):634–53.
  • 3.   Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis. 2012;54(Suppl 1):S23–34.
  • 4.   Sunil VJ, Swati SJ, Atul H, Snigdha AV, Divya B, Shubhang M. COVID-19 associated mucormycosis (CAM): a clinico-histopathological study at a tertiary care centre. Indian J Pathol Res Pract. 2022;11(1):19–26.
  • 5.   Jeong W, Keighley C, Wolfe R, Lee WL, Slavin MA, Kong DCM, et al. The epidemiology and clinical manifestations of mucormycosis: a systematic review and meta-analysis of case reports. Clin Microbiol Infect. 2019;25:26–34.
  • 6.   Jagtap SV, Jagtap SS, Nagar V, Varshney K. Invasive mucormycosis in post COVID-19 infection: case report with review. IP Arch Cytol Histopathol Res. 2021;6(2):135–9.
  • 7.   Karadeniz Uğurlu Ş, Selim S, Kopar A, Songu M. Rhino-orbital mucormycosis: clinical findings and treatment outcomes of four cases. Turk J Ophthalmol. 2015;45(4):169–74.
  • 8.   Bavikar P, Mehta V. Rhino-orbital-cerebral mucormycosis: a fatal complication of uncontrolled diabetes mellitus. Cureus. 2017;9(11):e1841.
  • 9.   Jagtap SV, Hulwan A, Vartak S, et al. Co-infection of mucormycosis and actinomycosis in COVID-19 infection. Int J Health Sci Res. 2021;11(8):127–30.
  • 10.   Galletti B, Gazia F, Galletti C, Perani F, Ciodaro F, Freni F, et al. Rhinocerebral mucormycosis with dissemination to pontine area in a diabetic patient: treatment and management. Clin Case Rep. 2019;7(7):1382–7.
  • 11.   Bhansali A, Bhadada S, Sharma A, et al. Presentation and outcome of rhino-orbital-cerebral mucormycosis in patients with diabetes. Postgrad Med J. 2004;80:670–4.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Jagtap SV, Jagtap SS, Borade DS, et al. Invasive mucormycosis in an adolescent female with type-I diabetes mellitus. Indian J Pathol Res Pract. 2023;12(1):29–33.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
November 23, 2022 December 28, 2022 January 30, 2023

DOI: 10.21088/ijprp.2278.148X.12123.4

Keywords

Rhinoorbital Infections.MucormycosisDiabetic KetoacidosisOpportunistic Infection

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Received November 23, 2022
Accepted December 28, 2022
Published January 30, 2023

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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