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Correlation Study of Fine Needle Aspiration Cytology of Thyroid Lesions With Thyroid Profile and Ultrasonography

Bindu B J, Nivedita Mallikarjun Mellihalli, Sharvani R Setty

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Indian Journal of Pathology: Research and Practice 11(4):p 139-145, October-December 2022. | DOI: https://doi.org/10.21088/ijprp.2278.148X.11422.2

How Cite This Article:

Nivedita Mallikarjun Mellihalli, Bindu B J, Sharvani R Setty/Correlation Study of Fine Needle Aspiration Cytology of Thyroid Lesions With Thyroid Profile and Ultrasonography/Indian Journal of Pathology: Research and Practice 2022;11(4) 139–145.

Timeline

Received : September 22, 2022         Accepted : October 25, 2022          Published : December 25, 2022

Abstract

Introduction: Fine needle aspiration cytology (FNAC) of thyroid is a minimally invasive, cost-effective and an easy to perform outpatient procedure. FNAC along with thyroid function test (TFT) and ultrasonography (USG) helps in proper preoperative assessment, changes clinical management and improves patient outcome. Objectives: 1. To study the cytological features of thyroid lesions using FNAC using. The Bethesda System for Reporting Thyroid Cytology. 2. To correlate thyroid cytology with thyroid hormonal status and USG. Materials/Methods: The study was conducted in the Department of Pathology from January 2020 to December 2020 and included 50 patients with thyroid lesions who underwent FNAC, thyroid function tests and USG. Lesions were evaluated cytologically and categorized according to Bethesda System of classification and correlated with Thyroid profile and USG. Results: Out of 50 cases, females were most affected (92%). Most affected age group was middle aged (21-50 yrs). Bethesda Category I to VI cases were 4%, 82%, 2%, 4%, 2% and 6% respectively. Colloid goitre was the most common among non-neoplastic lesions. Majority of the benign and all malignant lesions were euthyroid. Hypothyroidism was mostly seen in Hashimoto thyroiditis. In 92% of the cases, USG and FNAC diagnosis correlated well. Conclusion: FNAC is a simple diagnostic modality for thyroid lesions with high specificity. The study showed that cytological analysis in conjunction with thyroid profile and USG helps to make accurate diagnosis and determine the course of therapy in effective management of patients with thyroid lesions.


References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Nivedita Mallikarjun Mellihalli, Bindu B J, Sharvani R Setty/Correlation Study of Fine Needle Aspiration Cytology of Thyroid Lesions With Thyroid Profile and Ultrasonography/Indian Journal of Pathology: Research and Practice 2022;11(4) 139–145.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
September 22, 2022 October 25, 2022 December 25, 2022

DOI: https://doi.org/10.21088/ijprp.2278.148X.11422.2

Keywords

Fine Needle Aspiration Cytology (FNAC)ThyroidThyroid Function TestThe Bethesda System for Reporting Thyroid Cytology (TBSRTC)USG

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Received September 22, 2022
Accepted October 25, 2022
Published December 25, 2022

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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