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Histopathological Study of Granulomatous Lesions of the Skin at Tertiary Care Hospital

Dilip Sarate. , Ahilya Balaso Dhadas1 , Dilip Sarate2 , Pradeep Umap3 , Pradeep Male4

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Indian Journal of Pathology: Research and Practice 9(2 (Part-II)):p 137-144, May-August 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.22

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Ahilya Balaso Dhadas, Dilip Sarate, Pradeep Umap, Pradeep Male. Histopathological Study of Granulomatous Lesions of the Skin at Tertiary Care Hospital. Indian J Pathol Res Pract 2020;9(2 Part II):
137–144.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Granulomas are organized aggregates of macrophages and other immune cells often with characteristic morphological changes. Granulomas evolved as protective responses to destroy or sequester particles but are frequently pathological in the context of foreign bodies, infections, and inflammatory diseases. Cutaneous diseases occur in 60% to 70% of cases of granulomatous lesions. Present study aimed to study the morphology of cutaneous granulomatous lesions. Total 170 patients with clinical suspicion of granulomatous skin lesions were subjected for punch biopsy from skin lesion. Histopathological examination was done to study the morphology of lesion.
We found 148 cases of Leprosy, 11 cases of tuberculous of skin, 03 cases of actinomycosis and 8 cases were non infectious granulomatous lesions. Age group of the study population varies from 9 year to 69 years and had mean age 35.57 year. 106 were male and 64 were female. Upper limb (41%) followed by lower limb (19%) was the most
common site of biopsy. Clinically, hypopigmented patch (34%) followed by plaque (27%) was the most common presentation. Of the leprosy cases, borderline tuberculoid leprosy (BT- 45%) followed by tuberculoid leprosy (TT –14%) was the predominant lesion. Lupus vulgaris (56%) was the predominant tuberculous skin lesion.

Keywords: Actinomycosis; Biopsy; Borderline Tuberculoid; Granuloma; Leprosy; Lupus Vulgaris; Skin;Tuberculosis; Tuberculoid Leprosy.
 

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Cite this article

Ahilya Balaso Dhadas, Dilip Sarate, Pradeep Umap, Pradeep Male. Histopathological Study of Granulomatous Lesions of the Skin at Tertiary Care Hospital. Indian J Pathol Res Pract 2020;9(2 Part II):
137–144.
 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.22

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