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Analysis of Thrombocytopenia and Utility of Platelet Indices

Chaitra K. , Chaitra K1 , Janhavi M S2 , Smita Kadadavar

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Indian Journal of Pathology: Research and Practice 9(2 (Part-II)):p 145-148, May-August 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.23

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Chaitra K, Janhavi M S, Smita Kadadavar. Analysis of Thrombocytopenia and Utility of Platelet Indices. Indian J Pathol Res Pract 2020;9(2 Part II):145–148.
 

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Abstract

Background: Haematology analyser that determine Platelet indices, such as Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), Platelet-crit (PCT) and Platelet large cell ratio (P-LCR) may provide some valuable information regarding the underlying mechanism and pathogenesis of thrombocytopenia.


Methods: Prospective observational study of 200 thrombocytopenic samples, hemogram analysis done byautomated haematology analyser and Statistical analysis was done.


Results: Among the 200 cases of thrombocytopenia,66 cases were classified intohypo productive and 134 cases into hyper-destructive thrombocytopenia. Most common cause of hypo-productive and hyper-destructive was Megaloblastic anaemia(52%) and Dengue(42%) respectively. Both MPV and PDW were increased in hyperdestructive thrombocytopenia compared to hypo productive thrombocytopenia.
Conclusion: Increased MPV and PDW may provide a reliable positive diagnosis of Immune Thrombocytopenic Purpura in case of thrombocytopenic patients.


Keywords: Thrombocytopenia; Immune thrombocytopenia; Platelet indices; Mean platelet volume; Platelet
distribution width.
 

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Cite this article

Chaitra K, Janhavi M S, Smita Kadadavar. Analysis of Thrombocytopenia and Utility of Platelet Indices. Indian J Pathol Res Pract 2020;9(2 Part II):145–148.
 

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.23

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