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Histopathological Spectrum of Urinary Bladder Lesions With Focus on Neoplastic Lesions

S Susmitha , S Susmitha1 , Girija S Patil2 , SB Patil3

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Indian Journal of Pathology: Research and Practice 9(1(Part 2)):p 194-199, January – April 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.30

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S Susmitha, Girija S Patil, SB Patil. Histopathological Spectrum of Urinary Bladder Lesions With Focus on Neoplastic Lesions.
Indian J Pathol Res Pract. 2020;9(1 Part II):194–199.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

 

Introduction: Lesions of urinary bladder constitute an important
source of clinical signs and symptoms. Both neoplastic and nonneoplastic lesions do occur commonly, however the former being
the most common type. Majority of urinary tract tumors are
epithelial in origin, among which 90% of them are urothelial in
origin. Objective: To evaluate the histopathological spectrum of
urinary bladder lesions with emphasis on the neoplastic lesions
with reference to 2016 WHO classification of tumors of urinary
system. Materials and Methods: This was a prospective study and
includes all the urinary bladder specimens received. They were
examined grossly and processed completely as per the standard
procedure. Multiple sections of 3–5 microns were taken and
stained with H & E, followed by light microscopic examination
to study various non-neoplastic and neoplastic lesions. Results:
Total 65 cases were studied, 30 were cystoscopic biopsies and
35 were TURBT specimens. There were 40 males and 25 females
constituting up to 61.54% and 38.46% respectively. Chronic
non-specific cystitis was the common non-neoplastic lesion.
Among neoplastic lesion, Invasive urothelial carcinoma was
the predominant lesion constituting 22 cases (62.86%). These
neoplastic lesions were more common among males (74.28%)
with M:F ratio of 2.8:1. Conclusion: Urinary bladder lesions
are most frequently encountered by surgical pathologists and
are heterogenous. Both benign and malignant lesions are well
documented but latter being more common. Many of these are
more common in elderly people with male predilection and are
often associated with smoking. Identifying the extent of invasion
by microscopic examination constitutes an important aspect in
urothelial carcinomas.
Keywords: Urinary bladder; Cystoscopic biopsy; Transurethral
resection of bladder tumor; Invasive urothelial carcinoma.

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Cite this article

 

S Susmitha, Girija S Patil, SB Patil. Histopathological Spectrum of Urinary Bladder Lesions With Focus on Neoplastic Lesions.
Indian J Pathol Res Pract. 2020;9(1 Part II):194–199.

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Received Accepted Published
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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.30

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