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Morphological and Immunohistochemical Categorization of Malignant Lymphomas

Amita K , Roopa AN1 , Shameem Shariff2 , Amita K3 , Shilpa MD4

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Indian Journal of Pathology: Research and Practice 9(1(Part 2)):p 188-193, January – April 2020. | DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.29

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Roopa A.N, Shameem Shariff, Amita K, et al. Morphological and Immunohistochemical Categorization of Malignant Lymphomas.
Indian J Pathol Res Pract. 2020;9(1 Part II):188–193.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

 

Lymphomas are broadly classified in to Hodgkins lymphoma
(HL) and Non Hodgkins lymphoma. Immunohistochemistry
helps in better understanding of pathogenesis and also useful
in the characterization of immunophenotype in most of the
malignant lymphomas. Aims & Objectives: The current study
was undertaken to categorize malignant lymphomas based on
morphological and immunohistochemical findings. Materials
and Methods: Fifty cases of Lymphomas were diagnosed in the
Department of Pathology, at MVJ Medical College Research
Hospital, over a period of two year (between April 2015 and
April 2017). The data was analyzed with respect to age, sex,
histomophological and immunohistochemical characters.
Results: Out of 50 cases, 12 were of HL (24%) and 38 cases
(76%) were NHL. Among NHL, B-cell and T-cell lymphomas
were of equal incidence. Male’s outnumbered females (68%) &
maximum incidence of lymphomas including both sexes was
seen in age group 51-60 years followed by age group 41–50
years. Conclusion: IHC is a useful adjunct modality with H&E
stain in diagnosis and classification of malignant lymphomas.
Keywords: HL; NHL; T-cell; B-cell; RS cell.

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Cite this article

 

Roopa A.N, Shameem Shariff, Amita K, et al. Morphological and Immunohistochemical Categorization of Malignant Lymphomas.
Indian J Pathol Res Pract. 2020;9(1 Part II):188–193.

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9120.29

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