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Histopathological Spectrum of Pulmonary Lesions in Autopsies: A Two Year Retrospective Study

Syeda Husnain Fatima, Gayathri T, Shailaja Kupati, Shashikala V, Prathima S

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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

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Indian Journal of Forensic Medicine and Pathology 15(4):p 275-279, October-December 2022. | DOI: https://doi.org/10.21088/ijfmp.0974.3383.15422.10

How Cite This Article:

Fatima SH, Gayathri T, Kupati S, et al. Histopathological spectrum of pulmonary lesions in autopsies: a two year retrospective study. Indian J Forensic Med Pathol. 2022;15(4):275-279.

Timeline

Received : September 03, 2022         Accepted : December 06, 2022          Published : December 30, 2022

Abstract

Background: The lungs are secondarily involved in almost all forms of terminal events. Study of these lesions will help in devising prophylactic strategies to reduce associated mortality. Objectives: To find the frequency of various lung lesions in relation to age, sex, and to analyze histopathological spectrum of lung lesions in autopsy cases. Material and methods:Two years retrospective study based on hospital records from January 2019 - December 2020 carried out in department of pathology. Lungs were fixed in 10% formalin & processed. Paraffin wax embedding was done & sections stained with H & E stain. Gross and microscopic examination of samples were conducted for diagnosis. Results: A total of 147 cases with lung specimens were received during the period of study. Among these, 47 (32%) cases showed tissue autolysis of lung. The age ranged from 8 months to 80 years. Majority of cases analyzed were from adults, only 8 (5.5%) cases were below 15 years of age. Pathologies were detected in 99 cases and one case had unremarkable histology. Majority of the cases (77%) were males. Microscopic findings seen included congestion and edema (30%), inflammation (acute pneumonia, granulomatous and fungal) (23%), emphysema (20%), changes in interstitium (12%) and pulmonary thromboembolism (12%). Majority of the pulmonary thromboembolism were seen in the age group of 16-30 years. Conclusion: Congestion and edema followed by pneumonia were the most commonly observed pathological lung lesions in our study. Autopsy study of lung lesions can provide an insight to plan certain preventive strategies to reduce morbidity and mortality due to lung pathology

References

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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.

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Cite this article

Fatima SH, Gayathri T, Kupati S, et al. Histopathological spectrum of pulmonary lesions in autopsies: a two year retrospective study. Indian J Forensic Med Pathol. 2022;15(4):275-279.

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator

Received Accepted Published
September 03, 2022 December 06, 2022 December 30, 2022
DOI: https://doi.org/10.21088/ijfmp.0974.3383.15422.10

Keywords

AutopsyHistopathologyLung lesionsHistopathologyLung lesions

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Timeline

Received September 03, 2022
Accepted December 06, 2022
Published December 30, 2022

licence

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator


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