Abstract

Aim: This study aims to describe the clinical features, obstetric and neonatal outcome of pregnancies complicated with COVID-19 infection. Methods: This is a longitudinal, single center, observational study conducted on all COVID-19 positive pregnant women who were admitted in our institution from July 2020 to June 2021. During the study period, a total of 195 pregnant women with COVID-19 infection confirmed by RT PCR test, were admitted and included in the study. Data were collected about the demographic profile, clinical characteristics, maternal and neonatal outcomes. Results: The mean age was 26 years (SD = 3.48). Majority patients (75.4%) were asymptomatic and 21.5% had mild symptoms. Only 2(1.02%) women had severe COVID pneumonia. Majority (89.6%) were admitted in 3rd trimester. Cesarean section rate in COVID-19 infected pregnant women was 60%. Most neonates were asymptomatic and only 2 of them tested positive on testing within 48 h of birth. Conclusion: There is no major effect of COVID-19 infection during pregnancy on maternal and neonatal outcome.

• 1.   Nayak AH, Kapote DS, Fonseca M, Chavan N, Mayekar R, Sarmalkar M, et al. Impact of the coronavirus infection in pregnancy: A preliminary study of 141 patients. J Obstet Gynecol India 2020;70:25661. 24.
• 2.   Muhidin S, Behboodi Moghadam Z, Vizheh M. Analysis of maternal coronavirus infections and neonates born to mothers with 2019nCoV; A systematic review. Arch Acad Emerg Med 2020;8:e49.
• 3.   Ayed A, Embaireeg A, Benawadh A, AlFouzan W, Hammoud M, AlHathal M, et al. Maternal and perinatal characteristics and outcomes of pregnancies complicated with COVID-19 in Kuwait. BMC Pregnancy Childbirth 2020;20:19. 27.
• 4.   Smith V, Seo D, Warty R, Payne O, Salih M, Chin KL, et al. Maternal and neonatal outcomes associated with COVID-19 infection: A systematic review. PLoS One 2020;15:e0234187.
• 5.   Kumari A, Anand S, Vidyarthi A. Effects of COVID-19 during pregnancy on maternal and neonatal outcome: A retrospective observational study in tertiary teaching hospital, India. J Family Med Prim Care 2022;11:1820-5.
• 6.   Knight M, Bunch K, Vousden N, Morris E, Simpson N, Gale C, et al. Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. UK Obstetric Surveillance System BMJ. 2020;369:m2107.
• 7.   Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases. Am J Obstetr Gynecol 2020;223:111.e114.
• 8.   Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obstet Gynecol Scand 2020;99:8239.
• 9.   Zeng H, Xu C, Fan J, Tang Y, Deng Q, Zhang W, et al. Antibodies in infants born to mothers with COVID-19 pneumonia. JAMA 2020;323:18489.
• 10.   Antoun L, Toweel NE, Ahmed I, Patni S, Honest H. Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study. Eur J Obstet Gynecol Reprod Biol 2020;252:55962.

Data Sharing Statement

Funding