Rajeshwari L Khyade, Chandrajeetsingh Tale, Poonam Rayaskar
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Background: Fibromyoma, or uterine leiomyoma, is the most common benign tumor of the female reproductive tract, affecting 50-80% of women by age 50. Despite its benign nature, it poses a significant clinical dilemma due to its variable presentation, impact on quality of life, and complex management decisions. Aim: This article discusses the diagnostic and therapeutic dilemmas associated with fibromyoma, focusing on challenges in clinical decision-making for symptomatic women. Discussion: The dilemma arises from several factors. First, most fibroids are asymptomatic, yet 25-30% cause menorrhagia, pelvic pain, pressure symptoms, or reproductive issues. Second, treatment must balance symptom relief with fertility preservation. Options include expectant management, medical therapy with GnRH agonists or SPRMs, minimally invasive procedures like uterine artery embolization and HIFU, and surgical approaches such as myomectomy or hysterectomy. Each has distinct risks, benefits, and recurrence rates. Third, differentiating benign fibroids from the rare leiomyosarcoma (<1%) preoperatively remains challenging. Fourth, fibroids in pregnancy can lead to red degeneration, preterm labor, and postpartum hemorrhage, yet many women have uneventful outcomes. Conclusion: Managing fibromyoma requires individualized care based on age, symptoms, fertility desires, and fibroid characteristics. A multidisciplinary approach with thorough counseling is essential. Further research is needed for reliable biomarkers to rule out malignancy and long-term fertility data for newer modalities.
Rajeshwari L Khyade, Chandrajeetsingh Tale, Poonam Rayaskar. Fibromyoma: A Clinical Dilemma. Indian J Obstet Gynecol. 2026; 14(2): 69-72.
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| June 09, 2026 | July 14, 2026 | August 30, 2026 |
Tuesday 18 August 2026, 18:54:18 (IST)
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| Received | June 09, 2026 |
| Accepted | July 14, 2026 |
| Published | August 30, 2026 |
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.