Abstract

Hidradenitis suppurativa (HS), also referred to as Verneuil’s disease or acne inversa, derives its name from the Greek words hidros (sweat) and aden (glands).1 It is a chronic, scarring condition believed to result from the blockage of hair follicles, primarily affecting intertriginous and anogenital areas. While the axilla and groin are the most commonly affected regions, HS can also occur in the mammary and submammary areas, perineum, and sacral region. There is no standardized treatment, and in severe cases, extensive surgical excision followed by complex reconstructive procedures is necessary. One of the primary challenges post-excision is managing the resulting skin defects. While secondary healing may be an option, large defects require skin grafts or flaps to minimize scarring and accelerate recovery. When multiple anatomical regions are affected, staged surgical interventions may be required. Histopathology is gold standard for final diagnosis. Here we report a case of 27-year-old male with multiple abscesses over right axillary region diagnosed as Hidradenitis suppurativa.

• 1.   Lee EY, Alhusayen R, Lansang P, Shear N, Yeung J: What is hidradenitis suppurativa? Can Fam Physician, 2017; 63(2):114-120.
• 2.   Lin, M.; Breiner, M.; Fredricks, S. Marjolin’s ulcer occurring in hidradenitis suppurativa. Plast. Reconstr. Surg. 1999, 103, 1541–1543.
• 3.   McCarthy, S.; Foley, C.C.; Dvorakova, V.; Quinlan, C.; Murphy, M.; Maher, M. PASH syndrome with bony destruction. Clin. Exp. Dermatol. 2019, 44, 918–920.
• 4.   Jemec, G.; Thomsen, B.; Hansen, U. The homogeneity of hidradenitis suppurativa lesions. A histological study of intra-individual variation. APMIS 1997, 105, 378–383.
• 5.   Ward, R.A.; Udechukwu, N.S.; Selim, M.A.; Jaleel, T. Vulvar and perineal verrucous changes complicating hidradenitis suppurativa after wide excision: A case and literature review. Dermatol. Online J. 2020, 26, 13030.
• 6.   Vossen, A.R.J.V.; Schoenmakers, A.; van Straalen, K.; Prens, E.P.; Van Der Zee, H.H. Assessing pruritus in hidradenitis suppurativa: A cross-sectional study. Am. J. Clin. Dermatol. 2017, 18, 687–695.
• 7.   Boer, J.;Weltevreden, E. Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions. Br. J. Dermatol.1996, 135, 721–725.
• 8.   Attanoos, R.; Appleton, M.; Hughes, L.; Ansell, I.; Douglas-Jones, A.; Williams, G. Granulomatous hidradenitis suppurativa and cutaneous Crohn’s disease. Histopathology 1993, 23, 111–115.
• 9.   Chu, E.; Kovarik, C.; Lee, R. Lymphedematous verrucous changes simulating squamous cell carcinoma in long-standing hidradenitis suppurativa. Int. J. Dermatol. 2013, 52, 808–812.
• 10.   Page, M.J.; McKenzie, J.E.; Bossuyt, P.M.; Boutron, I.; Hoffmann, T.C.; Mulrow, C.D.; Shamseer, L.; Tetzlaff, J.M.; Akl, E.A.; Brennan, S.E.; et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ 2021, 372.
• 11.   Van der Zee, H.H.; Horvath, B.; Jemec, G.B.; Prens, E.P. The association between hidradenitis suppurativa and Crohn’s disease: In search of the missing pathogenic link. J. Investig. Dermatol. 2016, 136, 1747–1748.
• 12.   Kalen, J.E.; Shokeen, D.; Mislankar, M.;Wangia, M.; Motaparthi, K. Langerhans Cell Histiocytosis with Clinical and Histologic Features of Hidradenitis Suppurativa: Brief Report and Review. Am. J. Dermatopathol. 2018, 40, 502–505.

Data Sharing Statement

Funding