Zeeba S. Jairajpuri Professor, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India
Monal Trisal Assistant Professor, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India
Shaan Khetrapal Associate Professor, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New DelhiI, India
Nida Jalal Post Graduate 3rd Year Student, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India
Jyoti Mishra Professor, Department of Pathology, Kalyan Singh Government Medical College, Bulandshahar, Uttar Pradesh, India
Address for correspondence: Zeeba S. Jairajpuri, Professor, Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India E-mail: jairajpurizs@gmail.com
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Monal Trisal, Zeeba S. Jairajpuri, Shaan Khetrapal et al., A Rare Case Report of Primary Skin-Limited Leucocytoclastic Vasculitis:
A Diagnostic and Therapeutic Challenge. Ind Jr of Path: Res and Practice 2025;14(1) 31-34.
Timeline
Received : February 10, 2025
Accepted : March 05, 2025
Published : April 30, 2025
Abstract
Leucocytoclastic vasculitis (LCV) is a histopathologic term referring to small vessel vasculitis characterized by the infiltration of neutrophils and immune complex deposition. Clinically, LCV presents with palpable purpura, often involving the lower extremities, and may be associated with systemic involvement. We hereby report a rare case of LCV
in a 56 year female, highlighting clinical presentation and management strategies for the subset of LCV that remains confined to the skin without systemic manifestations posing diagnostic challenges.
References
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Monal Trisal, Zeeba S. Jairajpuri, Shaan Khetrapal et al., A Rare Case Report of Primary Skin-Limited Leucocytoclastic Vasculitis:
A Diagnostic and Therapeutic Challenge. Ind Jr of Path: Res and Practice 2025;14(1) 31-34.
This license
enables reusers to distribute, remix, adapt, and build upon the material in any
medium or format for noncommercial purposes only, and only so long as
attribution is given to the creator.
This license
enables reusers to distribute, remix, adapt, and build upon the material in any
medium or format for noncommercial purposes only, and only so long as
attribution is given to the creator.
Description: Photomicrograph of skin punch biopsy showing keratinized stratified squamous epithelium with mild basal layer pigment incontinence. (10x, H&E)
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Description: High power view exhibiting upper and deeper dermis with few dilated blood vessels showing mild mixed perivascular infiltration comprising of polymorph, lymphocytes, and few eosinophils along with cellular debris. (40x, H&E)