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Indian Journal of Obstetrics and Gynecology 14(1):p 29-32, Jan - April 2026. | DOI: 0.21088/ijog.2321.1636.14126.5
Case Report
When Eclampsia Strikes the Brain Twice
Shanthala S,, Banu K, Surya Krishnan C
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Obstetrics and Gynecology 14(1):p 29-32, Jan - April 2026. | DOI: 0.21088/ijog.2321.1636.14126.5
How Cite This Article:
Timeline
Received : April 13, 2026
Accepted : May 08, 2026
Published : May 30, 2026
Abstract
Eclampsia is an obstetric emergency in which there is new onset seizures in a woman with preeclampsia that cannot be attributed to any other neurological cause. This is a result of impaired uteroplacental blood flow, systemic endothelial dysfunction and dysregulation of cerebral blood flow. Posterior reversible encephalopathy syndrome (PRES) is a serious complication of eclampsia, which is characterized by vasogenic edema primarily in the posterior regions of the brain which presents clinically as seizures, headaches, visual abnormalities, and altered consciousness. The following case report discusses a 29-year-old G2A1 in her 30 weeks 5 days pregnancy with antenatal eclampsia as a sequalae of which she ended up in extremely preterm delivery, posterior reversible encephalopathy, hypoxic ischemic encephalopathy and her clinical improvement with the timely multidisciplinary management
References
- 1. Martini C, Saeed Z, Simeone P, Palma S, Ricci M, Arata A, et al. Preeclampsia: Insights into pathophysiological mechanisms and preventive strategies. Am J Prev Cardiol. 2025 Sep;23:101054. doi:10.1016/j.ajpc.2025.101054. .
- 2. HIE Help Center. High-Risk Pregnancy. [Internet]. [place unknown]: HIE Help Center; Available from: https://hiehelpcenter. org/medical/causes-risk-factors/high-riskpregnancy/
- 3. Cerebral Palsy Guide. Newborns With Hypoxic Ischemic Encephalopathy (HIE).
- 4. Patel AJ, Patel BS, Shah AC, Jani SK. Maternal and perinatal outcome in severe pre-eclampsia and eclampsia: a study of 120 cases at a tertiary health care center in Western India. Int J Reprod
Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study."
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| April 13, 2026 | May 08, 2026 | May 30, 2026 |
DOI: 0.21088/ijog.2321.1636.14126.5
Keywords
Antenatal EclampsiaPRESHIEHypertension in Pregnancy •High Risk PregnancySearch for Similar Articles
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Timeline
| Received | April 13, 2026 |
| Accepted | May 08, 2026 |
| Published | May 30, 2026 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
