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Tetanus Toxoid Immunization Induced Gullian Barre Syndrome during Early Second Trimester of Pregnancy: A Unique Clinical Presentation

Pushpa null, Kushwah Rohit, Sharma Ankita

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Journal of Nurse Midwifery and Maternal Health 11(1):p 47-51, Jan -April 2025. | DOI: https://doi.org/10.21088/jnmmh.2454.7506.11125.7

How Cite This Article:

Pushpa, Kushwah Rohit, Sharma Ankita. Tetanus Toxoid Immunization Induced Gullian Barre Syndrome during Early Second Trimester of Pregnancy: A Unique Clinical Presentation. J Nurse Midwifery Matern Health. 2025; 11(1): 47-51.

Timeline

Received : December 27, 2024         Accepted : February 03, 2025          Published : April 30, 2025

Abstract

Guillain-Barre syndrome (GBS) is a rare neurological disorder which manifests as a symmetrical motor paralysis that gradually ascends upward involving diaphragm and other respiratory muscles leaving the person unable to breathe on their own and landing upon catastrophe. A 23-year-old primigravida with 16 weeks of gestation presented to emergency room with bilateral progressive lower limb weakness, along with history of tetanus toxoid vaccination 4-5 days prior to this event. She developed respiratory failure in virtue of diaphragmatic involvement and was managed in critical care setting with airway management, ventilatory assistance along with multidisciplinary approach. She was successfully discharged from hospital after receiving immunoglobulin therapy and other supportive measures. Management of GBS in pregnancy has been discussed.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Pushpa, Kushwah Rohit, Sharma Ankita. Tetanus Toxoid Immunization Induced Gullian Barre Syndrome during Early Second Trimester of Pregnancy: A Unique Clinical Presentation. J Nurse Midwifery Matern Health. 2025; 11(1): 47-51.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
December 27, 2024 February 03, 2025 April 30, 2025

DOI: https://doi.org/10.21088/jnmmh.2454.7506.11125.7

Keywords

GBSPregnancyIntravenous immunoglobulinPlasma exchangeTetanus toxoid vaccination

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Received December 27, 2024
Accepted February 03, 2025
Published April 30, 2025

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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