Abstract

Childhood cancer represents a devastating diagnosis that not only disrupts the life of the affected child but also profoundly impacts parents, who are the primary caregivers. With nearly 400,000 new pediatric cancer cases reported worldwide each year, and about 50,000 in India alone, the burden extends far beyond medical treatment. Advances in oncology have significantly improved survival outcomes, yet the psychosocial consequences for parents remain underexplored, especially in low- and middle-income countries. Parents of children with cancer face considerable psychological distress, manifested through anxiety, depression, anticipatory grief, and post-traumatic stress symptoms. Such distress is particularly pronounced during diagnosis and active treatment but may persist for years, even after remission. The quality of life (QoL) of parents is significantly impaired across multiple domains physical, psychological, social, and financial. Mothers, often the primary caregivers, report higher levels of emotional distress and role strain, while fathers are more affected by economic responsibilities and occupational challenges. Coping mechanisms vary, ranging from problem-solving and spirituality to maladaptive avoidance strategies. Social and cultural factors further shape parental responses, influencing both resilience and vulnerability. Holistic nursing care plays a critical role in mitigating these challenges. Nurses, by virtue of their close and continuous interaction with families, are uniquely positioned to provide comprehensive support. Evidence-based strategies such as psychosocial assessment, counseling, stress management programs, mindfulnessbased interventions, and family-centered care are effective in reducing distress and enhancing QoL. Additionally, culturally sensitive approaches that integrate family beliefs and spiritual practices are essential in diverse contexts like India.

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