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Study of Thyroid Lesions in a Teaching Hospital with Cytopathology and Histopathology Correlation

Swathi Sreesailam , Seetha Vijayalakshmi1 , Swathi Sreesailam2 , Kanya Kumari3

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Indian Journal of Pathology: Research and Practice 8(5):p 655-660, September-October 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.21

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Seetha Vijayalakshmi, Swathi Sreesailam, Kanya Kumari. Study of Thyroid Lesions in a Teaching Hospital with Cytopathology and Histopathology Correlation. Indian J Pathol Res Pract. 2019;8(5):655–660.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Introduction: Thyroid lesions are common globally and also in India. Most of the lesions are non-neoplastic or benign but still there are chances of malignancy and hence most of the patients undergo initial FNAC test to ascertain the nature of lesion. Based on the FNAC report the necessity for surgery and extent of surgery are planned. Aim of the study: To study thyroid lesions on cytology and histopathology and also to study the correlation on cytology and histopathology. Materials and Methods: This was a prospective hospital based study. FNAC/thyroid cytology was done and studied in 143 patients. Out of 143 cases, histopathology examination was done in 63 cases and the findings were correlated. Results: For cytology, the patient age ranged from 12 years to 71 years and the male to female ratio was 0.3:1. Nodular/colloid goiter was the most common diagnosis reported on cytology. Cyto-histological correlation yielded sensitivity of 82.4% and the specificity of 91%. The positive predictive value and negative predictive value of cytology to detect thyroid malignancy was 88.6% and 85.9% respectively. Conclusion: Thyroid lesions are more common in the young adults and have a female preponderance. Cytology/FNAC study of thyroid has good sensitivity and specificity for determining the nature of lesions. FNAC procedure is rapid, simple, inexpensive tool and gives quicker diagnosis than the histopathology.

Keywords: Thyroid FNAC; Histopathology of thyroid; Thyroid cytology and histopathology correlation.

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Seetha Vijayalakshmi, Swathi Sreesailam, Kanya Kumari. Study of Thyroid Lesions in a Teaching Hospital with Cytopathology and Histopathology Correlation. Indian J Pathol Res Pract. 2019;8(5):655–660.
 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.21

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