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Spectrum of Histopathological and Clinical Features in Psoriasis and Other Papulosquamous Skin Disorders

Sushant Bhadane , Sapana Bhadane1 , Sushant Bhadane2

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Indian Journal of Pathology: Research and Practice 8(5):p 650-654, September-October 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.20

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Sapana Bhadane, Sushant Bhadane. Spectrum of Histopathological and Clinical Features in Psoriasis and Other Papulosquamous Skin Disorders. Indian J Pathol Res Pract. 2019;8(5):650–654.
 

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Abstract

Background: Papulosquamous diseases characterized by scaling papules or plaques compose the largest heterogenous group of diseases. Psoriasis is the prototype of a group of cutaneous disorders that show Psoriasiform epidermal hyperplasia. Aim: To determine the histopathological & clinical pattern of Psoriasis and other papulosquamous disorders. Materials and Methods: Histopathological study of Papulo-squamous skin disorders was conducted at Department of Pathology. Sixty one cases attending dermatology OPD and fulfilling inclusion and exclusion criteria were selected for study. Results: Psoriasis occurred in all age groups except below 10 years but was commonly seen in young and middle age groups. Pityriasis rosea, Lichen nitidus, Prurigo simplex and inflammatory linear verrucous epidermal nevus were seen in children and young adults. High predominance was observed in males for all conditions. Fourty seven out of 61 cases showed clinic-pathological correlation which accounted for 77.05% of total cases. Twenty cases of Psoriasis were studied. Most common findings were parakeratosis, acanthosis, Munro microabscesses, hypogranulosis, spongiform pustules and dermal inflammation. Conclusion: Overlapping of both clinical pattern and distribution of papulosquamous skin disorders, which often made clinical diagnosis difficult. Proper clinical observation and histomorphological study will give conclusive diagnosis.

Keywords: Lichen planus; Scaly plaques; Eruptions; Pityriasis; Dermatitis.

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Cite this article

Sapana Bhadane, Sushant Bhadane. Spectrum of Histopathological and Clinical Features in Psoriasis and Other Papulosquamous Skin Disorders. Indian J Pathol Res Pract. 2019;8(5):650–654.
 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.20

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