Abstract

Postpartum hypo-pituitarism is also termed as Sheehan’s Syndrome. Heavy bleeding during or after delivery leading to further necrosis of the pituitary gland are all characteristic seen in Sheehan’s Syndrome. It is commonly associated with hypo-volemic shock. The presentation of Sheehan’s Syndrome most commonly include amenorrhoea, hypoglycaemia, hypothyroidism along with agalactorrhea, also psychiatric manifestations like commonly as psychosis are seen though they are not uncommon to be seen. In developed countries owing to advances in services of obstetric care the occurrence of Sheehan’s Syndrome is seen relatively rare and is overall gradually decreasing worldwide. However, it can still be considered as common and relatively frequent seen in underdeveloped and developing countries. The diagnosis of Sheehan’s Syndrome is commonly late as it evolves slowly, reporting of psychoses are quite rarely seen in cases of Sheehan’s Syndrome. Herein in our study we discuss a case of 37 year old woman, diagnosis was psychotic disorder along with Sheehans Syndrome, diagnosed years later, with etiological aspects, follow-ups period and the details treatment with thyroxine, glucocorticoids which has shown a tremendous results with complete remission after attaining euthyroid and eucortisolemic state

• 1.   Ozkan Y, Colak R, Guardi M, Altunbas H, Balci MK, Karayalcin U. Sheehan’s syndrome: clinical and laboratory evaluation of 20 cases. Neuro Endocrinol Lett. 2005;26(3):257-60.
• 2.   Kelestimur F. Sheehan’s syndrome. Pituitary. 2003;6(4):181-8.
• 3.   Zargar AH, Singh B, Laway BA, Masoodi SR, Wani AI, Bashir MI. Epidemiological aspects of postpartum pituitary hypofunction (Sheehan’s syndrome). Fertil Steril. 2005;84(2):523-8.
• 4.   Abs R, Bengtsson BA, Hernberg-Stahl E, Monson JP, Feldt-Rasmussen U, Wilton P, et al. GH replacement in 1034 growth hormone deficient hypopituitary adults: demographic and clinical characteristics, dosing and safety. Clin Endocrinol (Oxf). 1999;50(6):703-13.
• 5.   Sheehan HL. The incidence of postpartum hypopituitarism. Am J Obstet Gynecol. 1954;68(1):202-23.
• 6.   Gei-Guardia O, Soto-Herrera E, Gei-Brealey A, Chen-Ku CH. Sheehan’s syndrome in Costa Rica: clinical experience on 60 cases. Endocr Pract. 2011;17(3):337-44.
• 7.   Shivaprasad C. Sheehan’s syndrome: newer advances. Indian J Endocrinol Metab. 2011;15(Suppl 3):S203-7.
• 8.   Kale K, Sahoo S, Bhatia S. Postpartum psychosis in a case of Sheehan’s syndrome. Indian J Psychiatry. 1999;41(1):70-2.
• 9.   Parry BL. Postpartum syndromes. In: Kaplan HI, Sadock BJ, editors. Comprehensive textbook of psychiatry. 6th ed. Vol. 1. Baltimore: Williams and Wilkins; 1995. p. 1059-66.
• 10.   Thomas MJ, Iqbal AS. Sheehan’s syndrome with psychosis. J Assoc Physicians India. 1985;33:175-6.

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