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Histopathological Patterns in Abnormal Uterine Bleeding at a Tertiary Hospital

Pradeep Jadhav, Associate Professor, Dept. of Pathology, American International Institute of Medical Sciences, Udaipur, Rajasthan 313001, India. , Pradeep Jadhav1 , Dipti Patel2 , S.N. Chawla3

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Indian Journal of Pathology: Research and Practice 7(6):p 754-757, June 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.7

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Abstract

Background: Abnormal uterine bleeding (AUB) is related with patient’s social,familial and personal life because of the considerable morbidity it causes. The aim of the study was to examine the histopathological patterns of endometrium in patients presenting with AUB as well as to find out its incidence in different age groups.

Materials and Methods: This is a retrospective study, conducted in the Department of Pathology, in a tertiary care teaching hospital, Udaipur from Jan. 2016 to Jan. 2018. The study includes cases of AUB with a probable endometrial cause.The study was done in the form of measures and percentages and showen as tables where found necessary.

Results: A total of 215 cases were studied.The age of the patients were from 18-72 years. Incidence of AUB was most common in the perimenopausal age group. Menorrhagia was the most common presenting complaint. Proliferative endometrium was the most common histopathological finding and was seen in 35.34% patients, followedby secretory endometrium in 18.60% patients, and disordered proliferative endometrium in 17.67% patients.Hyperplasia was seen in 16.73% cases. Malignancy was detected in 2.36% of cases and all were endometrial carcinoma.

Conclusions: Themain indication of endometrial biopsies is to rule out malignancy and endometrial hyperplasia in women over 35 years of age group. When no organic pathology was found,different physiological patterns like secretory phase,proliferative phase and other endometrial changes were observed. The most common endometrial pathology observed was proliferative phase endometrium.

Keywords: Abnormal Uterine Bleeding; Dilatation and Curettage; Endometrium.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.7

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