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Histomorphologic Spectrum of Pediatric Brain Tumours: Three Year Retrospective Study

Rohini Priya S., Assistant Professor, Department of Pathology, Govt Stanley Medical college, Chennai, Tamil Nadu 600001, India. , Vijay Sathish Kumar I.1 , Rohini Priya S.2

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Indian Journal of Pathology: Research and Practice 7(12):p 1247-1250, December 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.71218.11

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Abstract

Histomorphological study of pediatric brain tumours in children upto fourteen years was done in tertiary care centre for a period of three years. Supratentorial region was most common site. Astrocytoma was the most common tumour reported. Context: To understand the varied histomorphological spectrum of pediatric brain tumour in our setup. Aim: This is a retrospective study to analyse the histopathological profile of brain tumours in the age group upto fourteen years and statistically correlate the frequency of these tumours in the study with that of the literature and to report rare variants. Settings and Design: Observational study of histomorphology of pediatric brain tumours in a tertiary care centre for period of three years. Methods and Material: A total of 100 cases of brain tumours occuring in the age group upto fourteen years during the period from September 2015 to August 2018 were taken for study. Clinical, radiological and histopathological details collected. The tumours were classified according to World Health Organisation classification. The age, sex and site predilection of these tumours were studied along with histological typing. Statistical analysis used:- Results: In age group zero to four years we had 24 cases. In 5-10 years of age we had 45 cases. In 11-14 years we had 31 cases. 52.9% cases were supratentorial in location 47.10% cases were infratentorial. Conclusions: Paediatric Brain tumours were of higher incidence in the age group of five to ten years. Supratentorial tumours are more common than infratentorial. Astrocytoma was the leading brain tumour in paediatric age group except five to ten years where medulloblastoma was the leading one. Choroid plexus papilloma was found highest upto four years of age. Astrocytoma and ependymoma were common in male and Meningioma in female.Medulloblastoma, choroid plexus papilloma and craniopharyngioma have nearly equal distribution with mild male preponderance.

Keywords: Pediatric Brain Tumours; Histopathological Study. 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.71218.11

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