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Hematological Indices in Thyroid Disorders

K.R. Shouree, Post Graduate, Department of Pathology, Mysore Medical College and Research Institute, Mysore, Karnataka 570001, India. , K.R. Shouree1 , M. Bharathi2

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Indian Journal of Pathology: Research and Practice 7(6):p 764-767, June 2018. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.9

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Abstract

Context: Thyroid hormones are the important hormone helping in body metabolism. Every cell in the body depends on thyroid hormones for regulation of their metabolism. They are also known to play an important role in hematopoiesis. This study was done to know the impact of thyroid disorders like hypothyroidism and hyperthyroidism on various haematological indices which we see in routine complete blood count done using automated cell counter.

Aims: To study the effect of hypothyroidism and hyperthyroidism on various hematological indices.

Settings and Design: Prospective study Methods and Material: A total of 150 including 50 hypothyroid, 50 hyperthyroid and 50 control subjects were evaluated. A comparison was done on different parameters. 

Statistical analysis used: Results were reported as mean SD for variables. ANOVA and POST HOC test were used to calculate the significance of difference between two groups. P value <0.05 was considered as a significant change.

Results: A statistical difference was observed for MCV and MCH but other parameters did not show any statistically significant difference.

Conclusions: All the patients with thyroid disorders should be periodically evaluated for hematological changes.

Keywords: Thyroid Hormones; Hypothyroid; Hyperthyroid.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.7618.9

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