Abstract

Introduction: Pregnancy is an insulin resistant condition which allows physiologicaldyslipidemia to occur. This physiological dyslipidemia is essential for allowing fetal growth. However, when dyslipidemia crosses the physiological range, it predisposes the woman to preeclampsia development. Epigenetic reprogramming of the cells in the growing fetus increases the cardiovascular and metabolic complications in the adulthood. Material and methods: 330 antenatal patients were included in the study after matching inclusion and exclusion criteria. Lipid values were tested at 12-14 weeks of gestation and the women were followed up till delivery. Preeclampsia development was noted in women having deranged lipid values. Results: Of 330 antenatal patients enrolled in the study, 104 patients developed preeclampsia. All preeclampsia patients had hyperlipidemia in the 1st trimester. Conclusion: Early, cost-effective detection methods, management and timely delivery by outweighing risks of prematurity in baby and multiorgan failure,eclampsia and ultimately maternal mortality attributed to preeclampsia.

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