Abstract

Background: Due to wide spread uses in clinical sitting of different image modalities for example as ultrasound (US), CT scan (CT), and magnetic resonance image (MRI), lead to discover of many hidden liver lesions in previously un able to diagnosed. Imaging is a critical decision making tool in the diagnosis of liver lesion, because it will discriminate in high degree between malignant and benign in a lot of cases. Material and Methods: A crosssectional study were enrolled 67 patients with solid liver lesion whose admitted to Al-Hilla teaching Hospital between November 2018 and June 2019 with suspicion of solid live r lesion by ultrasound image or CT scan. Results: Sixtyseven patients (85 lesion) were included in this study. These patients aged between 25–70 years with mean age 52 ± 11 years. Study included 36 men (53.7%) and 31 women (46.3%). Male to female ratio 1.1:1. ADC values of 85 solid liver lesions were included in the study, an average of 1.2 lesion/patient. ADC range were 0.42–2.78 (10–3 mm2 /s) and ADC mean 1.2 ± 0.51(10-3 mm2 /s). The mean ADC and range for benign lesion was 1.7 ± 0.11 (0.72–2.78) and for malignant lesion was 0.61 ± 0.09 (0.42–1.68). Which is statistically significant difference between these value (p = 0.001). Conclusion: We concludes that quantitative assessment of solid liver lesion by DWI had best result in differentiate from benign and malignant lesion. The benign liver lesions had high ADC value than malignant lesion.

• 1.   Taj-Aldean KA. The Validity of Magnetic Resonance Imaging (MRI) in Characterizing Benign and Malignant Uterine Endometrial Cavity Masses. Res J Pharm BiolChe Sci. 2016; 7(6):750–54.
• 2.   N. Galea, V. Cantisani, B. Taouli. Liver lesion detection and characterization: Role of diffusionweighted imaging,J Magn Reson Imaging. 2013 Jun;37(6):1260-76
• 3.   Taj-Aldean KA. Role of diffusion weight in differential diagnosis of cerebral cystic lesion. A prospective study. Int J Pharm Clin Res. 2017:9(1):1–5.
• 4.   Ba-Ssalamah A, Baroud S, Bastati N and Qayyum A: MR Imaging of Benign Focal Liver Lesions, Magnetic Resonance Imaging Clinics of North America. 2010;(18):403–19.
• 5.   Caraiani C, Chiorean L, Fenesan DI, et al., Diffusion weighted magnetic resonance imaging for the classification of focal liver lesions as benign or malignant, J. Gastrointest. Liver Dis. 2015;9::309–17.
• 6.   Dietrich CF, Sharma M, Gibson RN. SchreiberDietrich D, Jenssen C.Fortuitously discovered liver lesions. World J Gastroenterol. 2013;19:3173–88.
• 7.   Chen L, Zhang J, Zhang L. Meta-analysis of gadoxetic acid disodium (Gd-EOB-DTPA)- enhanced magnetic resonance imaging for the detection of liver metastases. PLoS One. 2012;7:1–9.
• 8.   Jain TP, TerKan W, Edward S, et al. Evaluation of ADCratio on liver MRIdiffusion to discriminate benign versus malignant solid liver lesions. European Journal of Radiology Open. 2018;5:209–14.
• 9.   Chen ZG, Xu L, Zhang SW, et al. Lesion discrimination with breath-hold hepatic diffusion-weighted imaging: A meta-analysis, World J. Gastroenterol. 2015;21:1621–27.
• 10.   Li Y, Chen Z, Wang J. Differential diagnosis between malignant and benign hepatic tumors using Apparent diffusion coefficient on 1.5-T MR imaging: A meta analysis, Eur. J. Radiol. 2012;21:484–90.
• 11.   Taj-Aldean KA. Role of MRI in Comparison With DWI-MRI In Diagnosis of Intracranial Meningioma. A prospective study. Indian J Public Health Research & Development. 2018:9(10):336–41.
• 12.   Taouli B, Diffusion weighted MR imaging for liver characterization: a critical look. Radiology. 2012;262:378–80.
• 13.   Abdelsamed AM, Elia RZ, Hatim MA. The Role of Diffusion Weighted MRI in The Differentiation between Benign and Malignant Hepatic Focal Lesion The Egyptian Journal of Hospital Medicine 2017 Jul;68(2):;1176–83.
• 14.   Abdkadhim M, Hameed FS, Hussain MA. The Value of Diffusion Weighted MRI in Differentiating Benign from Malignant Solid Focal Liver Lesions. the Iraqi post graduate medical journal. 2016;15(1):91-101.
• 15.   Onura MR, Cicekcia M, Kayali A. The role of ADC measurement in differential diagnosis of focal hepatic lesions. European Journal of Radiology. 2012;81(3):171–76.
• 16.   Demir OI, Obuz F, Sagol O, et al. Contribution of diffusion-weighted MRI to the differential diagnosis of hepatic masses. Diagn Interv Radiol. 2007;13:81–86.
• 17.   Vergara ML, Fernández M and Pereira R. Diffusion-weighted MRI characterization of solid liver lesions, RevistaChilena De Radiología. 2010; 16(1):510.
• 18.   Testa ML, Chojniak R, Sene LS, et al. Is DWI/ADC a Useful Tool in the Characterization of Focal Hepatic Lesions Suspected of Malignancy? PLoS ONE. 2014;9(7):e101944.
• 19.   Culverwell A, Sheridan M, Guthrie J, et al., Diffusion weighted MRI of the liver - Interpretative pearls and pitfalls, Clin. Radiol. 2013;68:406–14.
• 20.   El-Badrawy A, Ashmallah GA, Tawfik AM et al. Diffusion-Weighted MR Imaging of the Benign Hepatic Focal Lesions. Open Journal of Radiology. 2014;4:136–43.
• 21.   Türkbey B., Aras Ö., Karabulut N, et al. DiffusionWeighted MRI for Detecting and Monitoring Cancer: A Review of Current Applications in Body Imaging. Diagnostic and Interventional Radiology. 2012;18:46–59.
• 22.   Goshima S, Kanematsu M, Kondo H, et al. Diffusion-Weighted Imaging of the Liver: Optimizing b Value for the Detection and Characterization of Benign and Malignant Hepatic Lesions. Journal of Magnetic Resonance Imaging. 2008;28:691–97.
• 23.   Kele PG and Van der Jagt E.J. Diffusion Weighted Imaging in the Liver. World Journal of Gastroenterology. 2010;16:1567–76.