Full Text (PDF)
Review Article

Detection of Mixed Profiling via Y-Filer Mode of Analyzation

Divya Tripathy, Sakshi Bhagoliwal1 null, M K Agarwal3 null

Author Information

Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Indian Journal of Forensic Medicine and Pathology 14(2 (Special Issue)):p 192-201, April-June 2021. | DOI: 10.21088/ijfmp.0974.3383.14221.26

How Cite This Article:

Bagholiwal S. Detection of mixed profiling via Y-Filer mode of analyzation. Indian J Forensic Med Pathol. 2021;14(2 Special):192-201.

Timeline

Received : April 02, 2021         Accepted : April 20, 2021          Published : June 30, 2021

Abstract

In this research study, we will look into the mixed profling via Y marker analysis in a sexual assault case. Background: Ascertaining the identifcation of the assailant or victim can be
determined conclusively by DNA profling of the samples found on the crime scene. Tere
are two types of DNA’s, nuclear DNA, and mitochondrial DNA. Generally, mitochondrial
DNA is taken in cases where nuclear DNA cannot be extracted which are mostly present
in hair and bone. Various types of DNA analysis, STR analysis, RFLP, mtDNA analysis, and
Y-fler depending on the case involved. In the cases involving mixed profling, it is Y-fler
profling which is used to fnd out the actual profle to give a report as conclusive evidence.
In this research, we will look at the analysis of mixed profling via Y-fler analysis in a sexual
assault case. Messages: Problem in the cases involving mixed gene analyzer profling that is
two accused involved in a particular crime scene becomes a condition whose admissibility
in the court comes under question. In such cases it is Y-chromosome present on “AMEL”
that is the locus studying for the X- and Y-chromosome signifying the presence or absence
of the criminal under question.
 


References

  • 1.   Butler JM. Forensic DNA typing: biology, technology, and genetics of STR markers. 2nd ed. London: Elsevier Academic Press; 2005.
  • 2.   Burke T, Dolf G, Jeffreys AJ, Wolff R, editors. DNA fingerprinting: approaches and applications. Basel: Birkhäuser Verlag; 1991.
  • 3.   Frye v. United States, 293 F. 1013 (D.C. Cir. 1923).
  • 4.   Butler JM. Forensic DNA typing: biology, technology, and genetics of STR markers. 2nd ed. London: Elsevier Academic Press; 2005.
  • 5.   Dash HR, Shrivastava P, Das S. Collection, transportation and preservation of biological evidences for DNA analysis. In: Dash HR, Shrivastava P, Lorente JA, editors. Principles and practices of DNA analysis: a laboratory manual for forensic DNA typing. Singapore: Springer; 2020. p. 23-38.
  • 6.   Chamoun CA, Couri MS, de Carvalho Queiroz MM, et al. Recovery and identification of human Y-STR DNA from immatures of Chrysomya albiceps (Diptera: Calliphoridae): simulation of sexual crime investigation involving victim corpse in state of decay. Forensic Sci Int. 2020;306:110068.
  • 7.   Frye v. United States, 293 F. 1013 (D.C. Cir. 1923).
  • 8.   Hill CR, Butler JM, Vallone PM. A 26plex autosomal STR assay to aid human identity testing. J Forensic Sci. 2009;54(5):1008-15.
  • 9.   Andrews v. State, 533 So. 2d 841 (Fla. Dist. Ct. App. 1988).
  • 10.   Dash HR, Shrivastava P, Lorente JA, editors. Principles and practices of DNA analysis: a laboratory manual for forensic DNA typing. Singapore: Springer; 2020.
  • 11.   Daubert v. Merrell Dow Pharmaceuticals, Inc., 509 U.S. 579, 113 S. Ct. 2786 (1993).
  • 12.   Aal-Hamdan HM, Refaat AM, Babu SR, Choudhry AR. Fetal gender determination through Y-STR analysis of maternal plasma during the third trimester of pregnancy. Egypt J Med Hum Genet. 2015;16(2):139-44.
  • 13.   Azmy O, El-Khayat W, Elias D, Abd-El-Karim M. Detection of cell free fetal DNA in plasma of pregnant women using multiplex quantitative fluorescent PCR. Med Res J. 2011;10(2):68-73.

About this article


Cite this article

Bagholiwal S. Detection of mixed profiling via Y-Filer mode of analyzation. Indian J Forensic Med Pathol. 2021;14(2 Special):192-201.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
April 02, 2021 April 20, 2021 June 30, 2021

DOI: 10.21088/ijfmp.0974.3383.14221.26

Keywords

dna profilingy-filermixed profiling

Article Level Metrics

Last Updated

Wednesday 08 July 2026, 06:29:44 (IST)


7722

Accesses

2
2137
00

Citations


NA
NA
NA

Download citation


Article Keywords


Keyword Highlighting

Highlight selected keywords in the article text.


Timeline


Received April 02, 2021
Accepted April 20, 2021
Published June 30, 2021

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Access this article



Share