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Correlation Between Imprint Cytology and The Histopathology of Breast Lesions

Manoj Sharma , Neil Sharma1 , Manoj Sharma2

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Indian Journal of Pathology: Research and Practice 8(5):p 690-696, September-October 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.27

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Neil Sharma, Manoj Sharma. Correlation Between Imprint Cytology and The Histopathology of Breast Lesions. Indian J Pathol Res Pract. 2019;8(5):690–696.
 

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: imprint cytology is a rapid and an accurate way for diagnosis of lesion especially in developing countries in the intraoperative setting where the facility of frozen section is not available. It is very accurate in differentiating between benign and malignant lesions and helps the surgeon to decide the future course of the surgery. Aims: to compare the accuracy of intraoperative imprints made with that of the histopathology Kal sections in breast lesions. Materials and methods: study of 50 cases of breast lesions were done at a tertiary care center comprising of the complete spectrum ranging from benign to malignant region and the findings were correlated with histological findings. Statistical methods: sensitivity, positive predictive value, negative predictive value, and specificity was calculated. Results: Our study included 50 benign and malignant lesions of the breast. On imprint cytology 17 cases were positive for malignancy, 28 cases were negative for malignancy and 5 cases were suspicious for malignancy. No false positive case was reported. All 5 cases which were reported as suspicious for malignancy were reported malignant on histopathology done after surgical biopsy. In the present study diagnostic sensitivity and specificity of imprint cytology was 77.28%, 100% respectively. There were 0% cases of false positive and 10% case of false negative. The negative predictive value was 84.84% and the positive predictive value was 100%. Conclusions: intraoperative imprint cytology is a very accurate tool in differentiating between benign and malignant lesions and can be easily applied in resource-poor and developing countries where the facility of the frozen section may not be available.

Keywords: Activated partial thromboplastin time; Platelet count; Prothrombin time; Type II Diabetes mellitus; SMIMER hospital Surat

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Cite this article

Neil Sharma, Manoj Sharma. Correlation Between Imprint Cytology and The Histopathology of Breast Lesions. Indian J Pathol Res Pract. 2019;8(5):690–696.
 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.27

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