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Comparative Study of Prothrombin Time, Activated Partial Thromboplastin Time and Platelet Counts in Type II Diabetes Mellitus and Healthy Individual

Toral Jivani , Hemaxi Patel1 , Toral Jivani2 , Purvi Patel3

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Indian Journal of Pathology: Research and Practice 8(5):p 686-689, September-October 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.26

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Hemaxi Patel, Toral Jivani, Purvi Patel. Comparative Study of Prothrombin Time, Activated Partial Thromboplastin Time and Platelet Counts in Type II Diabetes Mellitus and Healthy Individual. Indian J Pathol Res Pract. 2019;8(5):686–689.
 

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Abstract

Background: In diabetic patients incidence of cardiovascular disease due to thrombosis is higher than healthy individual. PT, aPTT and Platelet count are haematological parameters that give an idea about the coagulation status. So, this study aimed to assess the prothrombin time, activated partial thromboplastin time and platelet counts of type II diabetes mellitus patients. Methods: A comparative study was conducted at SMIMER hospital, Surat. A total 50 type II diabetic patients and 50 healthy control were included in this study. 4 ml of blood was collected in citrate bulb to determined PT, aPTT and Platelet count of these 2 Groups. Results: The mean aPTT of diabetic and healthy control 25.14 ± 6.32 and 35 ± 3.23 s, respectively. The proportion of diabetic patients with normal PT, aPTTand platelet counts was 84.0%, 10% and 92.0%, respectively. There was significant shortening of aPTT in Type II diabetic patients. Conclusions: There was a significant shortening of aPTT in diabetic patients as compared with non-diabetic groups. So, shortening of aPTT in untreated Type II diabetic patients might be useful marker in patients with diabetes and monitoring of the aPTT in newly diagnosed diabetic patients is important to prevent hypercoagulation.

Keywords: Activated partial thromboplastin time; Platelet count; Prothrombin time; Type II Diabetes mellitus; SMIMER hospital Surat.

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Hemaxi Patel, Toral Jivani, Purvi Patel. Comparative Study of Prothrombin Time, Activated Partial Thromboplastin Time and Platelet Counts in Type II Diabetes Mellitus and Healthy Individual. Indian J Pathol Res Pract. 2019;8(5):686–689.
 

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8519.26

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