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Indian Journal of Obstetrics and Gynecology 10(4):p 205-208, October-December 2022. | DOI: https://doi.org/10.21088/ijog.2321.1636.10422.4
Case Report
Acute Fatty Liver of Pregnancy: A Case Series
Suchita Dabhadkar, Neha Agarwal
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Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
Indian Journal of Obstetrics and Gynecology 10(4):p 205-208, October-December 2022. | DOI: https://doi.org/10.21088/ijog.2321.1636.10422.4
How Cite This Article:
Neha Agarwal, Suchita Dabhadkar/Acute Fatty Liver of Pregnancy: A Case Series/Indian J Obstet Gynecol. 2022;10(4):205–208.Timeline
Received : February 25, 2022
Accepted : March 22, 2022
Published : December 25, 2022
Abstract
Introduction: Acute fatty liver of pregnancy (AFLP), a rare but recognized obstetric and medical emergency, is a catastrophic illness for both the mother and unborn offspring. It develops rapidly in the last trimester of pregnancy and contributes to significant maternal and perinatal mortality. Its demands early diagnosis, immediate delivery of fetus, systematic approach for anticipating complications and dealing with them. Aim and Objective: To enlighten the varied presentations of this rare entity which help in early diagnosis, prompt delivery and highlighting the importance of supportive care to reduce maternal morbidity and mortality. Materials and Methods: The authors report an observational case series of patients who developed AFLP and were managed in critical care in a period of 3 months. Results: A total of three cases of AFLP were diagnosed in a period of 3 months. Nausea, vomiting and anorexia were the most common symptoms. Jaundice was seen in all. Anticipation of the complications like postpartum haemorrhage, DIC, hepatorenal syndrome and sepsis and providing prophylactic treatment in that view can reduce the morbidity and in-hospital days for the patient. Conclusions: AFLP has significant perioperative mortality and morbidity secondary to renal dysfunction, coagulopathy and massive transfusion related complications. Clinical outcome can be improved by early diagnosis, urgent delivery of fetus and supportive care from multidisciplinary team.
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Data Sharing Statement
There are no additional data available. All raw data and code are available upon request.
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
About this article
Cite this article
Neha Agarwal, Suchita Dabhadkar/Acute Fatty Liver of Pregnancy: A Case Series/Indian J Obstet Gynecol. 2022;10(4):205–208.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| February 25, 2022 | March 22, 2022 | December 25, 2022 |
DOI: https://doi.org/10.21088/ijog.2321.1636.10422.4
Keywords
Acute Fatty Liver of PregnancyPostpartum haemorrhageDICHepatorenal syndromeSepsisSearch for Similar Articles
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Timeline
| Received | February 25, 2022 |
| Accepted | March 22, 2022 |
| Published | December 25, 2022 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
