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Tuberculous Spondylodiscitis with Paraplegia in Pregnancy: A Rare Case Report

Vinitha Wills, Serene Mary Saji, Jacob Abraham

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Indian Journal of Obstetrics and Gynecology 10(4):p 211-215, October-December 2022. | DOI: https://doi.org/10.21088/ijog.2321.1636.10422.5

How Cite This Article:

Serene Mary Saji, Vinitha Wills, Jacob Abraham/Tuberculous Spondylodiscitis with Paraplegia in Pregnancy: A Rare Case Report/Indian J Obstet Gynecol. 2022;10(4):211–215.

Timeline

Received : August 06, 2022         Accepted : September 12, 2022          Published : December 25, 2022

Abstract

Tuberculosis continues to be a major health issue even now in a country like India due to its large population belonging to lower socioeconomic class. Tuberculous spondylodiscitis/Pott’s disease in pregnancy leading to paraplegia is uncommon and is a diagnostic and therapeutic challenge. According to World Health Organisation (WHO), TB is the third leading cause of death worldwide in women of reproductive age group. 21% of global burden of TB in pregnant women is in India. We report a case of a 28 year old, G3A2, at 29 weeks +3 days who presented with progressive bilateral upper limb and lower limb weakness and urinary incontinence. She was evaluated and was diagnosed to have Nurick Grade IV cervical compressive myelopathy with upper motor neuron (UMN) bladder due to tuberculous spondylodiscitis of C4 and C5 vertebrae. She underwent Elective lower segment caesarean section (LSCS) followed by 2 level C4-C5 corpectomy with expandable cage fusion and posterior stabilisation and fusion. Antitubercular regimen for 4 months was started thereafter. With a multidisciplinary approach, there was a good maternal and neonatal outcome. TB in pregnancy mandates early suspicion, diagnosis and treatment for timely intervention to prevent sequential complications to the mother and baby. So in high risk population clinicians should have a high index of suspicion of TB. We here aim to update the knowledge in early diagnosis and management of a rare case of Pott’s disease in the antenatal period which may help clinicians in their practice. Key message: Neurological manifestations in antenatal women especially in high risk groups for TB should prompt clinicians to consider a diagnosis of tuberculosis. Early initiation of anti-tuberculous drugs and if required adjunct surgery provides excellent maternal and neonatal outcome.


References

  • 1.   World Health Organization, Global tuberculosis report 2018, Geneva: World Health Organization; 2018.
  • 2.   India TB Report 2018.New Delhi: Central TB Division, Directorate General of Health Services, Ministry of Health and Family Welfare, Govt. of India;2018.
  • 3.   Dias HMY, PaiM, Raviglione MC. Ending tuberculosis in India: A political challenge and an opportunity. Indian J Med Res.2018; 147:217-220.
  • 4.   Yusuf, N., Ali, M., Ahmad, Q., Rahman, L., & Nigar, T. (2013). Pregnancy in Pott’s Disease: A Case Report and Review. Bangladesh Journal of Obstetrics & Amp; Gynaecology, 25(1), 37–40.
  • 5.   (Bates M, Ahmed Y, Kapata N et al. Perspectives on tuberculosis in pregnancy. International Journal of Infectious Diseases 32 (2015) 124–127).
  • 6.   Mathad JS, Gupta A. Tuberculosis in pregnant and postpartum women: Epidemiology, management, and research gaps. Clin Infect Dis. 2012;55:1532–49.
  • 7.   Miele K, Bamrah Morris S, Tepper NK. Tuberculosis in Pregnancy. Obstet Gynecol. 2020 Jun;135(6):1444- 1453. doi: 10.1097/AOG.0000000000003890. PMID: 32459437; PMCID: PMC7975823.
  • 8.   Loto OM, Awowole I. Tuberculosis in pregnancy: a review. J Pregnancy. 2012;2012:379271. doi: 10.1155/2012/379271. Epub 2011 Nov 1. PMID: 22132339; PMCID: PMC3206367.
  • 9.   van de Water, B.J., Brooks, M.B., Huang, CC. et al. Tuberculosis clinical presentation and treatment outcomes in pregnancy: a prospective cohort study. BMC Infect Dis 20, 686 (2020). https://doi.org/10.1186/s12879-020-054.
  • 10.   Jerker Jonsson, Sharon Kühlmann-Berenzon, Ingela Berggren, Judith Bruchfeld, Increased risk of active tuberculosis during pregnancy and postpartum: a register-based cohort study in Sweden European Respiratory Journal 2020 55: 1901886; DOI: 10.1183/13993003.01886-2019.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

Serene Mary Saji, Vinitha Wills, Jacob Abraham/Tuberculous Spondylodiscitis with Paraplegia in Pregnancy: A Rare Case Report/Indian J Obstet Gynecol. 2022;10(4):211–215.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
August 06, 2022 September 12, 2022 December 25, 2022

DOI: https://doi.org/10.21088/ijog.2321.1636.10422.5

Keywords

Tuberculous spondylodiscitisPott’s disease in pregnancyParaplegia in pregnancy

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Received August 06, 2022
Accepted September 12, 2022
Published December 25, 2022

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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