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Clinical Correlates of PCOS in A Tertiary Health Care Centre

Kiran Patole, Simran Singh

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Indian Journal of Obstetrics and Gynecology 10(1):p 25-34, January – March 2022. | DOI: https://doi.org/10.21088/ijog.2321.1636.10122.4

How Cite This Article:

How to cite this article: Simran Singh, Kiran Patole/Clinical Correlates of PCOS in A Tertiary Health Care Centre/ Indian J Obstet Gynecol. 2022;10(1):25–34.

Timeline

Received : August 20, 2021         Accepted : September 28, 2021          Published : March 30, 2022

Abstract

Aims: To study, analyse and find the correlation between different signs and symptoms of polycystic ovarian syndrome in a tertiary health care centre. Settings and Design: (1) Type of study: Observational Study (2) Sample size: 150 (3) Study participants: All patients attending gynaecology OPD diagnosed with PCOS. Study design: It was a Questionnaire based observational study. Methods and Material: This study was conducted on 150 patients of Polycystic Ovarian Syndrome. Diagnosis of Polycystic Ovarian Syndrome was done on the basis of 2003 Rotterdam diagnostic criteria. Ferriman Gallwey score was used for assessment of hirsutism and WHO cut-offs of Body Mass Index modified for Asian population was used for assessment of Body mass index, Statistical analysis used: Statistical Analysis: Data was compiled and analysed using site. Results: Percentages of Chief complaints: Irregular menses (89%), Obesity (41%), Hirsutism (37%), Acne (32% ), Infertility (10%). A Family History of Diabetes (45%), Hypertension 33%), Obesity (29%), Thyroid disorder (27%), PCOD (14%), Cardiac Disorder (13%) was also analysed. Polycystic changes in ultrasonographic findings were Present in 89% of the population and absent in 11% of the population. Only 33% participants were regular with the exercise routine rest. Hirsutism was graded according to mild (22%), moderate (62%), and severe (16%).50 % had Acne on examination. Body Mass Index was measured and graded into Underweight (11.3%), Normal (28.60%), Overweight (9.30%), Pre-obese (31.30%), Obese type 1 (19.30 %). Acanthosis nigricans (AN) was present in 32% And absent in 68%. There was significant Correlation between : ( p value <0.05) Irregular menses and infertility- 7%, Hirsutism and infertility- 3%, Ultrasonographic Findings and Acne- 48%, Obesity and Hirsutism- 45%, Irregular menses and acne - 48% Irregular menses and hirsutism- 33%, Ultrasonographic findings and acanthosis nigricans-29.3%. Conclusions: There is a diversity in the presentation of chief complaints of PCOS patients. PCOS patients show a variety in the presentation of the history of metabolic syndromes and of PCOS in their families. They show cutaneous manifestations in the form of Acne, Hirsutism and Acanthosis nigricans. PCOS patients mostly have moderate grades of hirsutism. Acne is present in almost half of PCOS patients even though most of them don't consider it as their chief complaint. Most of the participants who had increased BMI had Polycystic Ovarian Syndrome. Acanthosis is related to an increase in the BMI. Very few patients include exercise in their daily routine. There is a significant correlation in PCOS patients between: Irregular menses and infertility, Hirsutism and infertility, Ultrasonographic findings and Acne as chief complaint. Chief Complaints of Obesity and Chief Complaints of Hirsutism. Chief Complaints of irregular menses and Acne. Chief Complaints of Irregular menses and Hirsutism. Ultrasonographic findings and Acanthosis nigricans. Key Messages: This study has come up with the result of many statistically significant correlations between many common signs and symptoms like irregular menses, acne, hirsutism, infertility, Ultrasonographic findings, body mass index and acanthosis nigricans . Which will help in the further understanding of Polycystic ovarian syndrome. This study has also included various statistical analysis like having a family history of metabolic syndrome.


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Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

All authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

No conflicts of interest in this work.


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Cite this article

How to cite this article: Simran Singh, Kiran Patole/Clinical Correlates of PCOS in A Tertiary Health Care Centre/ Indian J Obstet Gynecol. 2022;10(1):25–34.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


Received Accepted Published
August 20, 2021 September 28, 2021 March 30, 2022

DOI: https://doi.org/10.21088/ijog.2321.1636.10122.4

Keywords

Polycystic ovarian syndromeAcneInfertilityHirsutismObesityFamily historyChief complaintsacanthosis nigricansIrregular menses

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Received August 20, 2021
Accepted September 28, 2021
Published March 30, 2022

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.


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