Abstract

Aims: To study, analyse and find the correlation between different signs and symptoms of polycystic ovarian syndrome in a tertiary health care centre. Settings and Design: (1) Type of study: Observational Study (2) Sample size: 150 (3) Study participants: All patients attending gynaecology OPD diagnosed with PCOS. Study design: It was a Questionnaire based observational study. Methods and Material: This study was conducted on 150 patients of Polycystic Ovarian Syndrome. Diagnosis of Polycystic Ovarian Syndrome was done on the basis of 2003 Rotterdam diagnostic criteria. Ferriman Gallwey score was used for assessment of hirsutism and WHO cut-offs of Body Mass Index modified for Asian population was used for assessment of Body mass index, Statistical analysis used: Statistical Analysis: Data was compiled and analysed using site. Results: Percentages of Chief complaints: Irregular menses (89%), Obesity (41%), Hirsutism (37%), Acne (32% ), Infertility (10%). A Family History of Diabetes (45%), Hypertension 33%), Obesity (29%), Thyroid disorder (27%), PCOD (14%), Cardiac Disorder (13%) was also analysed. Polycystic changes in ultrasonographic findings were Present in 89% of the population and absent in 11% of the population. Only 33% participants were regular with the exercise routine rest. Hirsutism was graded according to mild (22%), moderate (62%), and severe (16%).50 % had Acne on examination. Body Mass Index was measured and graded into Underweight (11.3%), Normal (28.60%), Overweight (9.30%), Pre-obese (31.30%), Obese type 1 (19.30 %). Acanthosis nigricans (AN) was present in 32% And absent in 68%. There was significant Correlation between : ( p value <0.05) Irregular menses and infertility- 7%, Hirsutism and infertility- 3%, Ultrasonographic Findings and Acne- 48%, Obesity and Hirsutism- 45%, Irregular menses and acne - 48% Irregular menses and hirsutism- 33%, Ultrasonographic findings and acanthosis nigricans-29.3%. Conclusions: There is a diversity in the presentation of chief complaints of PCOS patients. PCOS patients show a variety in the presentation of the history of metabolic syndromes and of PCOS in their families. They show cutaneous manifestations in the form of Acne, Hirsutism and Acanthosis nigricans. PCOS patients mostly have moderate grades of hirsutism. Acne is present in almost half of PCOS patients even though most of them don't consider it as their chief complaint. Most of the participants who had increased BMI had Polycystic Ovarian Syndrome. Acanthosis is related to an increase in the BMI. Very few patients include exercise in their daily routine. There is a significant correlation in PCOS patients between: Irregular menses and infertility, Hirsutism and infertility, Ultrasonographic findings and Acne as chief complaint. Chief Complaints of Obesity and Chief Complaints of Hirsutism. Chief Complaints of irregular menses and Acne. Chief Complaints of Irregular menses and Hirsutism. Ultrasonographic findings and Acanthosis nigricans. Key Messages: This study has come up with the result of many statistically significant correlations between many common signs and symptoms like irregular menses, acne, hirsutism, infertility, Ultrasonographic findings, body mass index and acanthosis nigricans . Which will help in the further understanding of Polycystic ovarian syndrome. This study has also included various statistical analysis like having a family history of metabolic syndrome.

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