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A Study of Multiple Congenital Anomalies in Fetus and Neonates

Kasturi Kshitija , Kasturi Kshitija1 , Seethamsetty Saritha2 , Sheshagiri Bhaskar3

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Indian Journal of Pathology: Research and Practice 8(4):p 449-457, July-August 2019. | DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8419.12

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Kasturi Kshitija, Seethamsetty Saritha, Sheshagiri Bhaskar. A Study of Multiple Congenital Anomalies in Fetus and Neonates. Indian J Pathol Res Pract. 2019;8(4):449–457.

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Received : N/A         Accepted : N/A          Published : N/A

Abstract

Background: Congenital Anomalies are one of the leading causes of paediatric mortality in developed & developing countries. Based on World Health Organization 3 million fetuses and infants are born each year with congenital anomalies. In India it is 6-7% which translates to around 1.7 million birth defects annually. This study was undertaken to present the spectrum of multiple congenital anomalies in fetus and neonates. Materials and Methods: This is a prospective based observational study done from March 2018 to March 2019. The data for the study was collected from a maternity hospital in Hyderabad. Autopsy was performed on dead fetuses and neonates with birth defects by a standard technique adopted by Edith L. Potter and was documented. Results: Of the total of 2043 pregnancies, 47 cases had multiple congenital anomalies with a prevalence of 2.3%. Of which 41 were fetal cases (87.23%) and 6 were neonatal cases (12.76%). Increase incidence of birth defects were noted in consanguinity, young primiparous and low socioeconomic group. Malformations of central nervous system (23.91%) was the commonest. Conclusions: Anomalous child has negative impact on mental status of the whole family. The outcome of our study is to initiate a national programme which focuses on prevention, care and surveillance for children born with birth defects.

Keywords: Congenital Anomalies; Birth defects; Fetus; Neonates.

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Kasturi Kshitija, Seethamsetty Saritha, Sheshagiri Bhaskar. A Study of Multiple Congenital Anomalies in Fetus and Neonates. Indian J Pathol Res Pract. 2019;8(4):449–457.

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DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.8419.12

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