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A Study of Cirrhotic Liver Associated with Extra Hepatic Vasculogenesis and Splenomegaly in Cadavers: with Clinical Correlation

V. Ujwala lakshmi

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Indian Journal of Anatomy 13(3):p 109-114, July - Sept. 2024. | DOI: https://doi.org/10.21088/ija.2320.0022.13324.4

How Cite This Article:

Lakshmi VU. A Study of Cirrhotic Liver Associated with Extra Hepatic Vasculogenesis and Splenomegaly in Cadavers: with Clinical Correlation. Indian J Anat. 2024; 13(3): 109-114.

Timeline

Received : August 03, 2024         Accepted : September 02, 2024          Published : November 30, 2024

Abstract

A Study of cirrhotic liver associated with extra hepatic vasculogenesis and splenomegaly in Cadavers: with Clinical Correlation.

Background: Cirrhosis is a consequence of chronic liver damage and inflammation and it is characterised by diffuse hepatic fibrosis and normal liver structures being replaced by regenerative liver nodules.7 Liver fibrosis in advanced states is critically important in the increased resistance, which leads into portal hypertension and splenomegaly.

Aims and Objectives:

To observe the prevalence of cirrhotic liver in south Indian population

To observe the association of cirrhotic liver with extra hepatic vasculogenesis and splenomegaly

Materials and Methods:

Observational descriptive study. 30 adult human embalmed cadavers were used for the study

Results and Conclusion:

Out of 30 cadavers one cadaver showed morphological changes of cirrhotic liver associated with splenomegaly. Prevalence of cirrhotic liver was 0.03%


References

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  • 4.   Ortiz-Olvera NX, et al. Anatomical cardiac alterations in liver cirrhosis: An autopsy study. Ann Hepatol. 2013; 12(3): 321-326.
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  • 6.   Wisse E, De Zanger RB, et al. Scanning electron microscope observations on the structure of portal veins, sinusoids and central veins in rat liver. Scanning Electron Microsc. 1983; 3: 1441-1452.
  • 7.   Liu YB, Chen MK. Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions. World J Gastroenterol. 2022; 28(41): 5910-5930.
  • 8.   Mak KM, Kee D, et al. A review of hepatic fibrosis-associated histopathology in aged cadavers. Anat Rec. 2023; 306(5): 1031-1053.

Data Sharing Statement

There are no additional data available. All raw data and code are available upon request.

Funding

This research received no funding.

Author Contributions

Whether all authors contributed significantly to the work and approve its publication.

Ethics Declaration

This article does not involve any human or animal subjects, and therefore does not require ethics approval.

Acknowledgements

We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.

Conflicts of Interest

The authors report no conflicts of interest in this work.


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Cite this article

Lakshmi VU. A Study of Cirrhotic Liver Associated with Extra Hepatic Vasculogenesis and Splenomegaly in Cadavers: with Clinical Correlation. Indian J Anat. 2024; 13(3): 109-114.


Licence:

Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



Received Accepted Published
August 03, 2024 September 02, 2024 November 30, 2024

DOI: https://doi.org/10.21088/ija.2320.0022.13324.4

Keywords

Cirrhotic liverAdeno carcinomaSplenomegaly

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Timeline


Received August 03, 2024
Accepted September 02, 2024
Published November 30, 2024

licence


Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.



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