Abstract

The increasing need for effective antimicrobial agents has become paramount due to the rising prevalence of antibiotic resistance among pathogens. In the current scenario, the overuse and misuse of antibiotics in clinical and agricultural settings have accelerated the development of resistant strains, creating an urgent demand for alternative therapies. Antibiosis, the mechanism by which antibiotics exert their effects, primarily involves inhibiting cell wall synthesis, disrupting protein production, or interfering with nucleic acid replication. While synthetic antibiotics have dominated the market, there is growing interest in natural sources of antibiotics, particularly plant-derived compounds. One such compound, eugenol, found in essential oils, has shown promising antimicrobial properties. Eugenol not only inhibits various foodborne pathogens but also enhances the efficacy of conventional antibiotics by lowering their minimum inhibitory concentration (MIC), making it a valuable candidate for use in combination therapies.

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