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Journal of Biochemistry and Biophysics 10(2):p 69-73, July-December 2025. | DOI: https://doi.org/10.21088/rfpjbb.2582-3558.10225.4
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The Unseen Pillars: The Foundational Role of Biophysics and Biochemistry in Modern Gynaecology and Obstetrics
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Journal of Biochemistry and Biophysics 10(2):p 69-73, July-December 2025. | DOI: https://doi.org/10.21088/rfpjbb.2582-3558.10225.4
How Cite This Article:
Alpana Saha, Pragati. The Unseen Pillars: The Foundational Role of Biophysics and Biochemistry in Modern Gynaecology and Obstetrics. RFP Jour. of Bio. and Biophy. 2025; 10(2): 69–73.Timeline
Received : September 26, 2025
Accepted : December 01, 2025
Published : December 25, 2025
Abstract
The clinical practice of gynaecology and obstetrics has historically been guided by anatomy, physiology, and empirical observation. However, the 21st century has witnessed a paradigm shift, revealing that the fundamental principles of biophysics and biochemistry are the unseen pillars supporting every aspect of female reproductive health. This article comprehensively reviews the critical importance of these disciplines in understanding and managing both normal physiological processes and pathological conditions. We explore the biophysical forces governing folliculogenesis, ovulation, and fallopian tube transport, alongside the intricate biochemical signaling of the hypothalamic-pituitary-ovarian (HPO) axis. In obstetrics, the roles of biochemical markers in prenatal screening and the biophysics of uteroplacental blood flow and fetal membrane integrity are examined. Furthermore, the article delves into the biophysical basis of diagnostic imaging, the biochemical pathogenesis of conditions like preeclampsia and endometriosis, and the revolutionary impact of biophysical techniques in assisted reproductive technologies (ART). The integration of biophysics and biochemistry is not merely ancillary but central to the advancement of personalized, predictive, and effective care in women’s health, paving the way for future innovations in diagnostics and therapeutics.
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There are no additional data available. All raw data and code are available upon request
Funding
This research received no funding.
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval.
Acknowledgements
We would like to express our gratitude to the patients, their families, and all those who have contributed to this study.
Conflicts of Interest
No conflicts of interest in this work.
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Cite this article
Alpana Saha, Pragati. The Unseen Pillars: The Foundational Role of Biophysics and Biochemistry in Modern Gynaecology and Obstetrics. RFP Jour. of Bio. and Biophy. 2025; 10(2): 69–73.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| September 26, 2025 | December 01, 2025 | December 25, 2025 |
DOI: https://doi.org/10.21088/rfpjbb.2582-3558.10225.4
Keywords
BiochemistryBiophysicsClinical PracticesGynaecologyParadigmSearch for Similar Articles
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Timeline
| Received | September 26, 2025 |
| Accepted | December 01, 2025 |
| Published | December 25, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
