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RFP Journal of Biochemistry and Biophysics 10(2):p 61-67, July-December 2025. | DOI: 10.21088/rfpjbb.2582-3558.10225.3
Original Article
Screen time and its Biochemical Effect on Human beings
Neha Suthar, Sachin C Narwadiya
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Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
RFP Journal of Biochemistry and Biophysics 10(2):p 61-67, July-December 2025. | DOI: 10.21088/rfpjbb.2582-3558.10225.3
How Cite This Article:
Narwadiya SC, Suthar N. Screen time and its biochemical effect on human beings. RFP Jour of Bio and Biophy. 2025;10(2):61–67.Timeline
Received : September 15, 2025
Accepted : October 30, 2025
Published : December 24, 2025
Abstract
Excessive screen exposure has become a major public health issue in the modern digital age, with increasing evidence associating long-term exposure to screens with a range of biochemical changes in human subjects. The current review study discusses the physiological and biochemical effects of prolonged exposure to electronic devices, including mechanisms like disruption of circadian rhythm, hormonal imbalance, oxidative stress, neurochemical modification, and metabolic dysregulation. Long-term exposure to blue light from screens is found to inhibit the production of melatonin, disrupting sleep and changing the hypothalamic-pituitary adrenal (HPA) axis. Sedentary lifestyle from screen time also leads to insulin resistance, higher cortisol levels, higher inflammatory markers (e.g., C-reactive protein, interleukins), and abnormalities in neurotransmitter homeostasis, such as the dopamine and serotonin pathways. These biochemical changes have been linked to sleep disorders, obesity, type 2 diabetes, mood dysregulation, and cognitive performance impairment. By integrating results from more current research, this review stresses the importance of evidence-based guidelines for modulating screen exposure and encouraging healthier digital life to counteract negative biochemical and physiological effects.
References
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Data Sharing Statement
There are no additional data available.
Funding
This research received no funding
Author Contributions
All authors contributed significantly to the work and approve its publication.
Ethics Declaration
This article does not involve any human or animal subjects, and therefore does not require ethics approval
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Cite this article
Narwadiya SC, Suthar N. Screen time and its biochemical effect on human beings. RFP Jour of Bio and Biophy. 2025;10(2):61–67.
Licence:
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
| Received | Accepted | Published |
|---|---|---|
| September 15, 2025 | October 30, 2025 | December 24, 2025 |
DOI: 10.21088/rfpjbb.2582-3558.10225.3
Keywords
Screen TimeBlue LightMelatonin SuppressionCircadian Rhythm• Oxidative StressCortisolNeurotransmittersSearch for Similar Articles
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Timeline
| Received | September 15, 2025 |
| Accepted | October 30, 2025 |
| Published | December 24, 2025 |
licence
Attribution-Non-commercial 4.0 International (CC BY-NC 4.0)
This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
